We investigate the mechanisms that control the spatio-temporal expression of genes operating in brain cortex development by using human brain organoids (self-organized 3D cultures derived from pluripotent stem cells that recapitulate brain structure development and inner organization) as a model system.

Our research focuses on cell replacement therapy as a treatment for neurological diseases like Parkinson's. We aim to understand how stem cells and replacement therapies can restore cellular functions and treat diseases. We explore the basic biology of stem cells and their potential to mature into functional neurons. Additionally, we're developing technologies for externally controllable bioimplants of therapeutic cells. Our goal is to enhance the treatment of neurodegenerative diseases through basic research and cell therapy.

Our laboratory is investigating the regulatory functions and mechanisms of cell signaling pathways through G proteins, particularly focusing on Gq protein-coupled receptors (GPCRs). We aim to understand how these pathways are involved in both normal physiological processes and pathological conditions. Our recent research has unveiled a new interaction region in Gαq, a subunit of G proteins, which plays a role in non-canonical Gq signaling and cell homeostasis.

The Epigenetics & Cellular Senescence lab is interested in understanding the basic mechanisms regulating cellular senescence and its influence on the microenvironment

The group studies active geological processes in the marine environment and their interrelationship with biodiversity.

The research group is created around the IEO Satellite Reception Station at the Santander Oceanographic Center, and its main objectives are doing research within the Initiatives of the European Space Agency (https://climate.esa.int/es /projects/) and university teaching on Remote Sensing at the Master's level.

The Marine Pollution Group of the IEO-CSIC is responsible for studying the environmental quality of the marine environment through the integration of chemical and biological parameters, determining the effects of pollutants on marine ecosystems, and establishing scientific bases to evaluate the effectiveness of measures to protect the marine environment and adequate coastal management. The group's strategic lines include the study of the spatial distribution and temporal trends of regulated and emerging pollutants in the marine environment; the study of the biological effects of chemical pollu

Research focus: Analysis and modeling of time series of physical, biological and biogeochemical variables especially based on sustained observations Coupled hydrodynamical-ecosystem models, physical-biological interactions Analysis of abundance, biomass, diversity and function of phyto-, zoo- and bacterioplankton Nutrient and greenhouse gas cycles, ocean acidification Analysis of food webs using stable isotopes Development of ocean services for marine users in aquaculture (e.g. harmful algal bloom forecasts) and fisheries