Pathophysiology of glycine transporters in glycinergic neurotransmission: hyperekplexia and pain

Pathophysiology of glycine transporters in glycinergic neurotransmission: hyperekplexia and pain


The group investigates glycinergic neurotransmission in health and different pathological scenarios such as hyperekplexia and pain. Hyperekplexia or startle disease (OMIM: 149400) is a rare neurological disorder, without specific treatment, characterized by pathological startle response to trivial stimuli that can be fatal in newborns. It is caused by the blockade of glycinergic inhibition by mutations in crucial synaptic proteins, such as the neuronal glycine transporter GlyT2. The aim is the search for personalized therapies for human hyperekplexia.

Main specialization

Functional analysis of proteins related to cell death in non-lethal biological scenarios.

Functional analysis of proteins related to cell death in non-lethal biological scenarios.


Numerous proteins initially identified as regulators of cell death programs appear to support basic cellular functions without inducing cell death. Leveraging our lab's expertise and resources, we aim to uncover the molecular regulation and implementation of these newly emerging non-lethal functions in both physiological and pathological contexts, with a special focus on the evolutionarily conserved caspase protein family.

Main specialization

Marine Biomolecules research group

Marine Biomolecules research group


Marine Biomolecules: Synthesis, Function and Exchange in Marine Systems The goal of the Marine Biomolecules group (BioMol) is to establish the role of different organic molecules (e.g., vitamins, pigments, etc.) in sustaining microbial communities and their impact on the natural biorhythmic fluctuations of the major biogeochemical cycles in marine systems.

Main specialization

Studies on Power and Culture in America (ÉPoCA)

Studies on Power and Culture in America (ÉPoCA)


This group studies the cultural, political, social, and economic realities of the Americas from an interdisciplinary approach focused on history and cultural criticism, with special attention to Atlantic world connections. Within this field, priority is given to three lines of research: • Line 1: Literary production, cultural history, politics and ideology in the Americas and contemporary Europe. • Line 2: Imaginaries and transfers in the Atlantic world: utopianism and political cultures. • Line 3: Construction of national states and Latin American integration.

Main specialization

LifeHub

LifeHub


Main specialization

Cultivation and experimentation of seaweeds

Cultivation and experimentation of seaweeds


Marine macroalgae (seaweeds) are a resource of great economic and environmental importance due to their numerous applications and key ecological functions. The scientific staff of the group has extensive expertise in studying both basic and applied of seaweeds, with a particular focus on kelps, through cultivation and experimentation. The overall objective is the research, development, and knowledge transfer in the cultivation, sustainable use, and conservation of seaweeds to contribute to addressing the current challenges of Marine Biotechnology within the framework of the EU Blue Growth St

Main specialization

BLUEFIN TUNA AND SIMILAR SPECIES BIOLOGY AND AQUACULTURE

BLUEFIN TUNA AND SIMILAR SPECIES BIOLOGY AND AQUACULTURE


Research group devoted to the study of the biology of bluefin tuna (Thunnus thynnus) and similar species (other scombrids, carangids such as Seriola dumerili, etc.) in captivity. It has the facilities of the Singular Scientific-Technical Infrastructure for Bluefin Tuna Farming (ICTS_ICAR), which it manages.

Main specialization

Electrochemical Devices Engineering and Fluid Dynamics Group

Electrochemical Devices Engineering and Fluid Dynamics Group


After several decades of research, fuel cells based on proton exchange membranes (PEMFCs) and redox flow batteries (BFRs) are at a stage in which their operating principles have already been fully demonstrated, but technological aspects still have significant deficiencies, which require further advances. To try to solve some of these problems, this research team explores the complex fluid dynamic processes taking place in both devices, through numerical simulations and experimental techniques.

Main specialization

Sustainable Marine Aquaculture and Biotechnology

Sustainable Marine Aquaculture and Biotechnology


The group's mission is to carry out research into the optimisation of integrated and sustainable farming of marine species and diversification in aquaculture, using a multidisciplinary approach and favouring the circular economy. To promote the sustainable exploitation of resources and the conservation of biodiversity.

Main specialization