The growth and diversification of the research lines of the "Biotechnology for lignocellulosic biomass" group has led to the creation of this new group, structured around two main line. Our common goal is focused on the bioconversion of natural or artificial waste by enzymes or whole microbial cells. Drs. Mª Jesús Martínez and Alicia Prieto lead studies on hydrolytic enzymes involved in the degradation and transformation of carbohydrates and lipids of the plant cell wall. On the other hand, Dr.

MitoPhenomics lab aims to understand the role of the small, understudied, circles of DNA in mitochondria (mtDNA) in metabolism and cell signaling in health and disease.

The "Nature, territory and cultural imaginaries" Research Group focuses its work on the relationships between physical environment, human action and cultural processes in different periods and historical contexts. The spatial planning processes have been accompanied by the production of collective imaginaries, which have conditioned the link that human societies maintain with nature. The RG investigates the role that the different uses of water and fossil fuels have had in the configuration of historical landscapes, cultural cosmovisions and socio-environmental metabolism.

Group Members: Mª José Motilva Casado: Research Scientist, CSIC (Responsible for Polyphenols) Mar Vilanova de la Torre: Distinguished Researcher, CSIC (Responsible for Volatiles area) Silvia Yuste: Postdoctoral researcher Bianca Souza: Researcher Juana I.

We focus in assessing the effect of forest management on forest system dynamics, the development of forest models and different actions linked to mitigation and adaption of forests to climate change.

Our research line is focused on elucidating the molecular mechanisms involved in the development of giant cell arteritis. Specifically, the main objective of our research group is to determine the genetic and epigenetic contribution to the pathogenesis of this disease by using genomic (genome-wide association studies, GWAS), epigenomic (DNA methylation and chromatin conformation analysis by ATAC-seq and ChIP-seq) and transcriptomic (RNA sequencing and single-cell RNA sequencing) approaches in cell types with a relevant role in giant cell arteritis.

The research of our group focuses primarily on two key areas within Phytopathology and Plant Bacteriology. The first line of work is aimed at the identification and characterization of bacteria, with the purpose of developing useful tools for diagnosing plant diseases and identifying those capable of causing diseases in plants. By creating rapid and accurate diagnostic methods, we aim to facilitate early detection and control of these diseases, helping to reduce economic losses and promote more sustainable agricultural practices.

The Castaño group is devoted to the advancement of the numerica methods for cryo electron tomography, including all aspects of the pipeline: alignment, reconstruction, particle location, subtomogram averaging and classification. This includes exploring protocols for cooperative use of further imaging techniques from Structural and Cellular biology (as superresolution light microscopy) towards the integration of information on multiple scales in space and time, aiming at the completion of mechanistic studies of key life processes. The group is commited to the production of robust, user-friendl

Our research explores the interface between chemical biology, medicinal chemistry and supramolecular chemistry. We use modern analytical techniques to study dynamic combinatorial libraries: dynamic networks of interchanging chemical species. We apply these dynamic networks as a hit-identification tool in drug discovery to gain insight into diseases’ etiology and study the properties derived from the molecular networks in the emerging field of systems chemistry to mimic functions encountered in Nature.