Iron oxide nanoparticles (IONP) doped with Galium (Ga) and Zinc (Zn) (GaZn-IONP), which have application as positive contrast agents in magnetic resonance imaging (MRI), in particular as positive contrast agents (T1-MRI).
Novel DNA probes useful for the rapid detection of SARS-CoV2, influenza and respiratory syncytial viral RNAs. Integrated in different set of devices, these probes enable the detection of RNA sequences in few minutes, without the need for RNA extraction, purification and PCR amplification
Portable diagnostic device for the detection of analytes in biological samples. The biosensor allows a label-free quantitative detection. Simple use, no qualified personnel needed.
Low-cost method with high effectiveness for the diagnosis and prognosis of thyroid cancers that are difficult to resolve during preoperative evaluation. It provides a malignancy score measuring the methylation level of various CpG sites determined by a machine learning classification system.
A signal amplification method for the simultaneous detection of respiratory RNA viruses in complex samples. The combination of molecular beacon technology and enzymatic digestion has proved to be a highly specific, cost-effective and fast alternative for detecting viral pathogens.
System based on an algorithm that allows for highly accurate diagnosis of breast cancer through the analysis of stochastic intracellular fluctuations of tumor cells, using images obtained through digital microscopy.
Immunochemical method for diagnosis of infections produced by Pseudomonas aeruginosa targeting the main signalling molecules of the pqs Quorum Sensing system. The immunoassay is fast and efficient, with low LOD and adaptable to point-of-care devices.
Early and accurate diagnosis and follow up of diseases related to cystine accumulation, such as cystinosis and cystinuria, based on a molecular network producing a signal measurable by fluorescence when certain substances bind to cysteine or cystine, allowing abnormal levels of cystine to be detected.