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Type III intermediate filaments as targets and effectors of electrophiles and oxidants

2020 Redox Biology
Volume:
36
Initial page:
101582
End page:
-
Authors:
Álvaro Viedma-Poyatos;María A Pajares;Dolores Pérez-Sala

Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency

2020 Frontiers in Pharmacology
Volume:
11
Initial page:
189
End page:
-
Authors:
María A. Pajares;Tahl Zimmerman;Francisco J. Sánchez-Gómez;Adriana Ariza;María J. Torres;Miguel Blanca;F. Javier Cañada;María I. Montañez;Dolores Pérez-Sala

Protein-protein interactions involving enzymes of the mammalian methionine and homocysteine metabolism

2020 Biochimie
Volume:
173
Initial page:
33
End page:
47
Authors:
Portillo, F.;Vázquez, J.;Pajares, M.A.

Interplay between nutrition and hearing loss: State of art.

2019 Nutrients
Volume:
11
Initial page:
35
End page:
-
Authors:
Puga, A. M.;Pajares, M. A.;Varela-Moreiras, G.;Partearroyo, T.

Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions

2019 Free Radical Biology and Medicine
Volume:
-
Initial page:
-
End page:
-
Authors:
Zorrilla, S.;Mónico, A.;Duarte, S.;Rivas, G.;Pérez-Sala, D.;Pajares, M.A.

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

2019 Redox Biology
Volume:
23
Initial page:
-
End page:
-
Authors:
Andreia Mónico;Sofia Duarte;María A. Pajares;Dolores Pérez-Sala

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division.

2019 Nature Communications
Volume:
10
Initial page:
4200
End page:
-
Authors:
Duarte, S.;Viedma-Poyatos A.;Navarro-Carrasco, E.;Martínez, A.E.;Pajares, M.A.;Pérez-Sala, D.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated to plasma hyperhomocysteinemia.

2019 FASEB Journal
Volume:
33
Initial page:
5942
End page:
5956
Authors:
Partearroyo T;Murillo-Cuesta S;Vallecillo N;Bermúdez-Muñoz JM;Rodríguez-de la Rosa L;Mandruzzato G;Celaya AM;Zeisel SH;Pajares MA;Varela-Moreiras G;Varela-Nieto I.

Mammalian sulfur amino acid metabolism: a nexus between redox regulation, nutrition, epigenetics and detoxification.

2018 Antioxidants & Redox Signaling
Volume:
29
Initial page:
408
End page:
452
Authors:
Pajares, M.A.;Pérez-Sala, D.

Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels.

2018 Human Mutation
Volume:
39
Initial page:
1081
End page:
1091
Authors:
García-Martín, E.;Sánchez-Gómez, F.J.;Amo, G.;García Menaya, J.;Cordobés, C.;Ayuso, P.;Plaza Serón M.C.;Blanca, M.;Campo, P.;Esguevillas, G.;Pajares, M.A.;Agúndez, J.A.G.;Pérez-Sala, D.

Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase.

2018 PLoS ONE
Volume:
13
Initial page:
e0199472
End page:
-
Authors:
Garrido, F.;Pacheco, M.;Vargas-Martínez, R.;Velasco-García, R.;Jorge, I.;Serrano, H.;Portillo, F.;Vázquez, J.;Pajares, M.A.

PDRG1 (p53 and DNA damage-regulated gene 1) at the interface between intermediary metabolism and oncogenesis.

2017 World Journal of Biological Chemistry
Volume:
8
Initial page:
175
End page:
186
Authors:
María Ángeles Pajares

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss

2017 Frontiers in Molecular Neuroscience
Volume:
10
Initial page:
107
End page:
-
Authors:
Teresa Partearroyo;Néstor Vallecillo;María A. Pajares;Gregorio Varela-Moreiras;Isabel Varela-Nieto

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

2017 Biochimica et Biophysica Acta - Molecular Cell Research
Volume:
1864
Initial page:
1165
End page:
1182
Authors:
Pérez-Miguelsanz, J.;Vallecillo, N.;Garrido, F.;Reytor, E.;Pérez-Sala, D.;Pajares, M.A.

The oncogene PDRG1 is an interaction target of methionine adenosyltransferases.

2016 PLoS ONE
Volume:
11
Initial page:
-
End page:
-
Authors:
Claudia Pérez;Francisco J. Pérez-Zúñiga;Francisco Garrido;Edel Reytor;Francisco Portillo;María A. Pajares

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice

2016 Frontiers in Aging Neuroscience
Volume:
8
Initial page:
-
End page:
-
Authors:
Raquel Martínez-Vega;Silvia Murillo-Cuesta;Teresa Partearroyo;Gregorio Varela-Moreiras;Isabel Varela-Nieto;María A. Pajares

The new levels of redox regulation of S-adenosylmethionine synthesis

2016 Anales de la Real Academia Nacional de Farmacia
Volume:
82
Initial page:
243
End page:
258
Authors:
Pajares, M.Á.

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and AldoseReductase

2016 Frontiers in Pharmacology
Volume:
7
Initial page:
-
End page:
-
Authors:
Francisco J. Sánchez-Gómez;Beatriz Díez-Dacal;ElenaGarcía-Martín;José A. G. Agúndez;Maria A. Pajares;Dolores Pérez-Sala

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism

2015 FASEB Journal
Volume:
29
Initial page:
418
End page:
432
Authors:
Martínez-Vega, R.;Garrido, F.;Partearroyo, T.;Cediel, R.;Zeisel, S.H.;Martínez-Álvarez, C.;Varela-Moreiras, G.;Varela-Nieto, I.;Pajares, M.A.

Long-term omega-3 fatty acid supplementation ameliorates cochlear homocysteine metabolism and progressive hearing loss in mice.

2015 Journal of Nutritional Biochemistry
Volume:
26
Initial page:
1424
End page:
1433
Authors:
Martínez-Vega, R.;Murillo-Cuesta, S.;Partearroyo, T.;Varela-Moreiras, G.;Varela-Nieto, I.;Pajares, M.A.

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.

2014 FASEB Journal
Volume:
29
Initial page:
-
End page:
-
Authors:
Martínez-vega, R;Garrido, F;Partearroyo, T;Cediel, R;Zeisel, SH;Martínez-Álvarez, C;Varela-Moreiras, G;Pajares, MA;varela-nieto, i.

Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes

2014 Antioxidants & Redox Signaling
Volume:
20
Initial page:
2541
End page:
2554
Authors:
Delgado, M.;Garrido, F.;Pérez-Miguelsanz, J.;Pacheco, M.;Partearroyo, T.;Pérez-Sala, D.;Pajares, M.A.

HOW ARE MAMMALIAN METHIONINE ADENOSYLTRANSFERASES REGULATED IN THE LIVER? A FOCUS ON REDOX STRESS.

2013 FEBS Letters
Volume:
587
Initial page:
1711
End page:
1716
Authors:
María A. Pajares;Luis Álvarez;Dolores Pérez-Sala

Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs

2013 Inflammation and Allergy - Drug Targets
Volume:
12
Initial page:
162
End page:
171
Authors:
Sánchez-Gómez FJ;García Dorado C;Ayuso P;Agúndez JAG;Pajares MA;Pérez-Sala D

NADP + Binding to the Regulatory Subunit of Methionine Adenosyltransferase II Increases Intersubunit Binding Affinity in the Hetero-Trimer

2012 PLoS ONE
Volume:
7
Initial page:
null
End page:
-
Authors:
González, B.;Garrido, F.;Ortega, R.;Martínez-Júlvez, M.;Revilla-Guarinos, A.;Pérez-Pertejo, Y.;Velázquez-Campoy, A.;Sanz-Aparicio, J.;Pajares, M.A.

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride

2012 Amino Acids
Volume:
42
Initial page:
361
End page:
373
Authors:
Garrido, F;Taylor, JC;Alfonso, C;Markham, GD;Pajares, MA

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride.

2012 Amino Acids
Volume:
42
Initial page:
361
End page:
373
Authors:
Garrido, F.;Taylor, J.C.;Alfonso, C.;Markham, G.D.;Pajares, M.A.

The relationship between human mat1a mutations and disease: A folding and association problem?

2011 Proteomics Research Journal
Volume:
2
Initial page:
451
End page:
478
Authors:
Pajares, M.A.;Pérez, C.

Refolding and characterization of methionine adenosyltransferase from Euglena gracilis

2011 Protein Expression and Purification
Volume:
79
Initial page:
128
End page:
136
Authors:
Garrido, F. ; Estrela, S. ; Alves, C. ; Sánchez-Pérez, G.F. ; Sillero, A. ; Pajares, M.A.

Methionine adenosyltransferase (s-adenosylmethionine synthetase)

2011 Advances in Enzymology and Related Areas of Molecular Biology
Volume:
78
Initial page:
449
End page:
-
Authors:
Pajares MA ; Markham GD

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1

2010 Molecular Pharmacology
Volume:
78
Initial page:
723
End page:
733
Authors:
Sánchez-Gómez, F.J.;Díez-Dacal, B.;Pajares, M.A.;Llorca, O.;Pérez-Sala, D.

Structure-function relationships in methionine adenosyltransferases

2009 Cellular and Molecular Life Sciences
Volume:
66
Initial page:
636
End page:
648
Authors:
Markham, G.D. ; Pajares, M.A.

Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution

2009 FASEB Journal
Volume:
23
Initial page:
3347
End page:
3360
Authors:
Reytor, E. ; Pérez-Miguelsanz, J. ; Alvarez, L. ; Pérez-Sala, D. ; Pajares, M.A.

Subunit association as the stabilizing determinant for archaeal methionine adenosyltransferases

2009 Biochimica et Biophysica Acta - Proteins and Proteomics
Volume:
1794
Initial page:
1082
End page:
1090
Authors:
Garrido, F. ; Alfonso, C. ; Taylor, J.C. ; Markham, G.D. ; Pajares, M.A.

Early effects of copper accumulation on methionine metabolism

2008 Cellular and Molecular Life Sciences
Volume:
65
Initial page:
2080
End page:
2090
Authors:
Delgado, M. ; Pérez-Miguelsanz, J. ; Garrido, F. ; Rodríguez-Tarduchy, G. ; Pérez-Sala, D. ; Pajares, M.A.

Betaine homocysteine S-methyltransferase: Just a regulator of homocysteine metabolism?

2006 Cellular and Molecular Life Sciences
Volume:
63
Initial page:
2792
End page:
2803
Authors:
Pajares, M.A. ; Pérez-Sala, D.

Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: Insights into intermediate structure through tryptophan substitutions

2005 Biochemical Journal
Volume:
391
Initial page:
589
End page:
599
Authors:
Garrido, F. ; Gasset, M. ; Sanz-Aparicio, J. ; Alfonso, C. ; Pajares, M.A.

Crystal structure of rat liver betaine homocysteine S-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding

2004 Journal of Molecular Biology
Volume:
338
Initial page:
771
End page:
782
Authors:
González, B.;Pajares, M.A.;Martínez-Ripoll, M.;Blundell, T.L.;Sanz-Aparicio, J.

Methionine adenosyltransferase α-helix structure unfolds at lower temperatures than β-sheet: A 2D-IR study

2004 Biophysical Journal
Volume:
86
Initial page:
3951
End page:
3958
Authors:
Iloro, I.;Chehín, R.;Goñi, F.M.;Pajares, M.A.;Arrondo, J.-L.R.

Cu2+ binding triggers αBoPrP assembly into insoluble laminar polymers

2004 FEBS Letters
Volume:
556
Initial page:
161
End page:
166
Authors:
González-Iglesias, R.;Elvira, G.;Rodríguez-Navarro, J.A.;Vélez, M.;Calero, M.;Pajares, M.A.;Gasset, M.

Methionine adenosyltransferase as a useful molecular systematics tool revealed by phylogenetic and structural analyses

2004 Journal of Molecular Biology
Volume:
335
Initial page:
693
End page:
706
Authors:
Sánchez-Pérez, G.F. ; Bautista, J.M. ; Pajares, M.A.

Role of an intrasubunit disulfide in the association state of the cytosolic homo-oligomer methionine adenosyltransferase

2003 Journal of Biological Chemistry
Volume:
278
Initial page:
7285
End page:
7293
Authors:
Sánchez-Pérez, G.F. ; Gasset, M. ; Calvete, J.J. ; Pajares, M.A.

Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism

2003 Journal of Molecular Biology
Volume:
331
Initial page:
407
End page:
416
Authors:
González, B. ; Pajares, M.A. ; Hermoso, J.A. ; Guillerm, D. ; Guillerm, G. ; Sanz-Aparicio, J.

Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase

2003 Biochemical Journal
Volume:
370
Initial page:
945
End page:
952
Authors:
González, B.;Campillo, N.;Garrido, F.;Gasset, M.;Sanz-Aparicio, J.;Pajares, M.A.

Leishmania donovani methionine adenosyltransferase: Role of cysteine residues in the recombinant enzyme

2003 European Journal of Biochemistry
Volume:
270
Initial page:
28
End page:
35
Authors:
Pérez-Pertejo, Y. ; Reguera, R.M. ; Villa, H. ; García-Estrada, C. ; Balaña-Fouce, R. ; Pajares, M.A. ; Ordóñez, D.

Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites

2002 Biochemical Journal
Volume:
361
Initial page:
307
End page:
315
Authors:
Gasset, M. ; Alfonso, C. ; Neira, J.L. ; Rivas, G. ; Pajares, M.A.

Priones: agentes causales de las encefalopatías espongiformes transmisibles.

2002 Medicina Clinica
Volume:
119
Initial page:
4
End page:
6
Authors:
González-Iglesias, R.;Espinosa, J. C.;Rodríguez, J. A.;Borniquel, S.;Elvira, G.;Pajares, M. A.;Gasset, M..

Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver

2002 Acta Crystallographica Section D: Biological Crystallography
Volume:
58
Initial page:
1507
End page:
1510
Authors:
González, B. ; Pajares, M.A. ; Too, H.-P. ; Garrido, F. ; Blundell, T.L. ; Sanz-Aparicio, J.

Prion protein interaction with glycosaminoglycan occurs with the formation of oligomeric complexes stabilized by Cu(II) bridges

2002 Journal of Molecular Biology
Volume:
319
Initial page:
527
End page:
540
Authors:
González-Iglesias, R.;Pajares, M.A.;Ocal, C.;Carlos Espinosa, J.;Oesch, B.;Gasset, M.

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

2000 European Journal of Biochemistry
Volume:
267
Initial page:
132
End page:
137
Authors:
Martínez-Chantar, M.L. ; Pajares, M.A.

The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site

2000 Journal of Molecular Biology
Volume:
300
Initial page:
363
End page:
375
Authors:
González, B. ; Pajares, M.A. ; Hermoso, J.A. ; Alvarez, L. ; Garrido, F. ; Sufrin, J.R. ; Sanz-Aparicio, J.

Refolding and characterization of rat liver methionine adenosyltransferase from Escherichia coli inclusion bodies

2000 Protein Expression and Purification
Volume:
19
Initial page:
219
End page:
226
Authors:
López-Vara, M.C. ; Gasset, M. ; Pajares, M.A.

Recombinant rat liver S-adenosyl-L-methionine synthetase tetramers and dimers are in equilibrium

1997 International Journal of Biochemistry and Cell Biology
Volume:
29
Initial page:
485
End page:
491
Authors:
Mingorance, J. ; Alvarez, L. ; Pajares, M.A. ; Mato, J.M.

S-adenosylmethionine synthesis: Molecular mechanisms and clinical implications

1997 Pharmacology and Therapeutics
Volume:
73
Initial page:
265
End page:
280
Authors:
Mato, J.M. ; Alvarez, L. ; Ortiz, P. ; Pajares, M.A.

Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression

1997 Endocrinology
Volume:
138
Initial page:
1251
End page:
1258
Authors:
Gil, B. ; Pajares, M.A. ; Mato, J.M. ; Alvarez, L.

Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity

1997 Journal of Biological Chemistry
Volume:
272
Initial page:
22875
End page:
22883
Authors:
Alvarez, L. ; Sánchez-Góngora, E. ; Mingorance, J. ; Pajares, M.A. ; Mato, J.M.

Site-directed mutagenesis of rat liver S-adenosylmethionine synthetase: Identification of a cysteine residue critical for the oligomeric state

1996 Biochemical Journal
Volume:
315
Initial page:
761
End page:
766
Authors:
Mingorance, J. ; Alvarez, L. ; Sánchez-Góngora, E. ; Mato, J.M. ; Pajares, M.A.

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

1996 FEBS Letters
Volume:
397
Initial page:
293
End page:
297
Authors:
Martínez-Chantar, M.L. ; Pajares, M.A.

Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis

1996 Journal of Hepatology
Volume:
25
Initial page:
200
End page:
205
Authors:
Gassó, M. ; Rubio, M. ; Varela, G. ; Cabré, M. ; Caballería, J. ; Alonso, E. ; Deulofem, R. ; Camps, J. ; Giménez, A. ; Pajares, M. ; Parés, A. ; Mato, J.M. ; Rodés, J.

Increased sensitivity to oxidative injury in Chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA

1996 Biochemical Journal
Volume:
319
Initial page:
767
End page:
773
Authors:
Sánchez-Góngora, E. ; Pastorino, J.G. ; Alvarez, L. ; Pajares, M.A. ; García, C. ; Viña, J.R. ; Mato, J.M. ; Farber, J.L.

Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development

1996 Hepatology
Volume:
24
Initial page:
876
End page:
881
Authors:
Gil, B.;Casado, M.;Pajares, M.A.;Boscá, L.;Mato, J.M.;Martín-Sanz, P.;Alvarez, L.

Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP

1995 Biochemical Journal
Volume:
308
Initial page:
565
End page:
571
Authors:
Deigner, H.P. ; Mato, J.M. ; Pajares, M.A.

Expression of rat liver S-adenosylmethionine synthetase in Escherichia coli results in two active oligomeric forms

1994 Biochemical Journal
Volume:
301
Initial page:
557
End page:
561
Authors:
Alvarez, L. ; Mingorance, J. ; Pajares, M.A. ; Mato, J.M.

S-adenosyl-L-methionine synthetase and methionine metabolism deficiencies in cirrhosis.

1994 Advances in Experimental Medicine and Biology
Volume:
368
Initial page:
113
End page:
117
Authors:
Mato, J. M.;Alvarez, L.;Ortiz, P.;Mingorance, J.;Durán, C.;Pajares, M. A.

Protein kinase C phosphorylation of rat liver S-adenosylmethionine synthetase: Dissociation and production of an active monomer

1994 Biochemical Journal
Volume:
303
Initial page:
949
End page:
955
Authors:
Pajares, M.A. ; Duran, C. ; Corrales, F. ; Mato, J.M.

Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

1992 Journal of Biological Chemistry
Volume:
267
Initial page:
17598
End page:
17605
Authors:
Pajares, M.A. ; Duran, C. ; Corrales, F. ; Pliego, M.M. ; Mato, J.M.

How is rat liver S-adenosylmethionine synthetase regulated?

1992 FEBS Letters
Volume:
309
Initial page:
1
End page:
4
Authors:
Pajares, M.A. ; Corrales, F. ; Duran, C. ; Mato, J.M. ; Alvarez, L.

Impairment of Methionine Metabolism in Liver Disease

1992 Clinical Drug Investigation
Volume:
4
Initial page:
8
End page:
13
Authors:
Corrales, F.;Alvarez, L.;Pajares, M.A.;Ortiz, P.;Mato, J.M.

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S- adenosylmethionine synthetase inactivation and attenuates liver injury

1992 Hepatology
Volume:
16
Initial page:
1022
End page:
1027
Authors:
Corrales, F. ; Gimenez, A. ; Alvarez, L. ; Caballeria, J. ; Pajares, M.A. ; Andreu, H. ; Pares, A. ; Mato, J.M. ; Rodes, J.

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the M(r) deduced from the cDNA sequence and the purified enzyme

1991 FEBS Letters
Volume:
290
Initial page:
142
End page:
146
Authors:
Alvarez, L. ; Asuncion, M. ; Corrales, F. ; Pajares, M.A. ; Mato, J.M.

Inhibition of glutathione synthesis in the liver leads to S-adenosyl-L-methionine synthetase reduction

1991 Hepatology
Volume:
14
Initial page:
528
End page:
533
Authors:
Corrales, F. ; Ochoa, P. ; Rivas, C. ; Martin-Lomas, M. ; Mato, J.M. ; Pajares, M.A.

The role of cysteine-150 in the structure and activity of rat liver S-adenosyl-L-methionine synthetase

1991 Biochemical Journal
Volume:
274
Initial page:
225
End page:
229
Authors:
Pajares, M.A. ; Corrales, F.J. ; Ochoa, P. ; Mato, J.M.

Fourier transform infrared studies of active-site-methylated rhodopsin -Implications for chromophore-protein interaction, transducin activation, and the reaction pathway.

1991 Biophysical Journal
Volume:
59
Initial page:
640
End page:
644
Authors:
Ganter, U. M.;Longstaff, C.;Pajares, M. A.;Rando, R. R.;Siebert, F.

Inactivation and dissociation of S-adenosylmethionine synthetase by modification of sulfhydryl groups and its possible occurrence in cirrhosis

1990 Hepatology
Volume:
11
Initial page:
216
End page:
222
Authors:
Corrales, F. ; Cabrero, C. ; Pajares, M.A. ; Ortiz, P. ; Martin-Duce, A. ; Mato, J.M.

Mechanisms and consequences of the impairment of the Trans-sulphuration pathway in liver disease.

1990 Drugs
Volume:
40
Initial page:
58
End page:
64
Authors:
Mato, J. M.;Corrales, F.;Martín-Duce, A.;Ortiz, P.;Pajares, M. A.;Cabrero, C.

Mechanisms and Consequences of the Impaired Trans-Sulphuration Pathway in Liver Disease: Part I: Biochemical Implications

1990 Drugs
Volume:
40
Initial page:
58
End page:
64
Authors:
Mato, J.M.;Corrales, F.;Martin-Duce, A.;Ortiz, P.;Pajares, M.A.;Cabrero, C.

Calcium-dependent binding between calmodulin and lysozyme.

1989 FEBS Letters
Volume:
247
Initial page:
22
End page:
24
Authors:
Fierro, J. F.;Pajares, M. A.;Hardisson, C.

The active-site environment of rhodopsin.

1989 Journal of Biological Chemistry
Volume:
264
Initial page:
6804
End page:
6809
Authors:
Pajares, M. A.;Rando, R. R.

The structural basis of protein kinase C activation by tumor promoters.

1989 Proceedings of the National Academy of Sciences of the United States of America
Volume:
86
Initial page:
9672
End page:
9676
Authors:
Nakamura, H.;Kishi, Y.;Pajares, M. A.;Rando, R. R.

-Alteraciones de la SAM-sintetasa hepática en cirrosis humana: implicación de los grupos sulfidrilo en la actividad y estructura de la enzima.

1989 Gastroenterologia y Hepatologia
Volume:
12
Initial page:
437
End page:
441
Authors:
Corrales, F.;Martín-Duce, A.;Pajares, M. A.;Ortiz, P.;Mato, J. M.

Protein Kinase C catalyzes the phosphorylation and activation of rat liver phospholipid methyltransferase.

1987 Biochemical Journal
Volume:
241
Initial page:
911
End page:
916
Authors:
Villalba, M. T;Pajares, M. A.;Renart, M. F.;Mato, J. M.

Purification of phospholipid methyltransferase from rat liver microsomes.

1986 Biochemical Journal
Volume:
237
Initial page:
699
End page:
705
Authors:
Pajares, M. A.;Villalba, M. T.;Mato, J. M.

Modulation by the ratio S-adenosylmethionine/S-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase.

1985 Biochimica et Biophysica Acta
Volume:
847
Initial page:
273
End page:
279
Authors:
Villalba, M. T.;Varela, I.;Mérida, I.;Pajares, M. A.;Martínez del Pozo, A.;Mato, J. M.

Activation of partially purified rat liver lipid methyltransferase by phosphorylation.

1984 Biochemical and Biophysical Research Communications
Volume:
122
Initial page:
1065
End page:
1070
Authors:
Varela, I.;Mérida, I.;Pajares, M.;Villalba, M. T.;Mato, J. M.

How many phospholipid methyltransferases are there in mammalian cells?

1984 Trends in Biochemical Sciences
Volume:
9
Initial page:
471
End page:
472
Authors:
Mato, J.M.;Pajares, M. A.;Varela, I.

Purification and photoaffinity labeling of lipid methyltransferase from rat liver.

1984 Biochemical Journal
Volume:
223
Initial page:
61
End page:
66
Authors:
Pajares, M. A.;Alemany, S.;Varela, I.;Marín Cao, D.;Mato, J. M.