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Type III intermediate filaments as targets and effectors of electrophiles and oxidants

2020 Redox Biology

Volumen:

Pagina Inicial:

101582

Pagina Final:

Autores:
Álvaro Viedma-Poyatos;María A Pajares;Dolores Pérez-Sala

Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency

2020 Frontiers in Pharmacology

Volumen:

Pagina Inicial:

189

Pagina Final:

Autores:
María A. Pajares;Tahl Zimmerman;Francisco J. Sánchez-Gómez;Adriana Ariza;María J. Torres;Miguel Blanca;F. Javier Cañada;María I. Montañez;Dolores Pérez-Sala

Protein-protein interactions involving enzymes of the mammalian methionine and homocysteine metabolism

2020 Biochimie

Volumen:

173

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Autores:
Portillo, F.;Vázquez, J.;Pajares, M.A.

Interplay between nutrition and hearing loss: State of art.

2019 Nutrients

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Autores:
Puga, A. M.;Pajares, M. A.;Varela-Moreiras, G.;Partearroyo, T.

Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions

2019 Free Radical Biology and Medicine

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Autores:
Zorrilla, S.;Mónico, A.;Duarte, S.;Rivas, G.;Pérez-Sala, D.;Pajares, M.A.

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

2019 Redox Biology

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Autores:
Andreia Mónico;Sofia Duarte;María A. Pajares;Dolores Pérez-Sala

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division.

2019 Nature Communications

Volumen:

Pagina Inicial:

4200

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Autores:
Duarte, S.;Viedma-Poyatos A.;Navarro-Carrasco, E.;Martínez, A.E.;Pajares, M.A.;Pérez-Sala, D.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated to plasma hyperhomocysteinemia.

2019 FASEB Journal

Volumen:

Pagina Inicial:

5942

Pagina Final:

5956

Autores:
Partearroyo T;Murillo-Cuesta S;Vallecillo N;Bermúdez-Muñoz JM;Rodríguez-de la Rosa L;Mandruzzato G;Celaya AM;Zeisel SH;Pajares MA;Varela-Moreiras G;Varela-Nieto I.

Mammalian sulfur amino acid metabolism: a nexus between redox regulation, nutrition, epigenetics and detoxification.

2018 Antioxidants & Redox Signaling

Volumen:

Pagina Inicial:

408

Pagina Final:

452

Autores:
Pajares, M.A.;Pérez-Sala, D.

Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels.

2018 Human Mutation

Volumen:

Pagina Inicial:

1081

Pagina Final:

1091

Autores:
García-Martín, E.;Sánchez-Gómez, F.J.;Amo, G.;García Menaya, J.;Cordobés, C.;Ayuso, P.;Plaza Serón M.C.;Blanca, M.;Campo, P.;Esguevillas, G.;Pajares, M.A.;Agúndez, J.A.G.;Pérez-Sala, D.

Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase.

2018 PLoS ONE

Volumen:

Pagina Inicial:

e0199472

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Autores:
Garrido, F.;Pacheco, M.;Vargas-Martínez, R.;Velasco-García, R.;Jorge, I.;Serrano, H.;Portillo, F.;Vázquez, J.;Pajares, M.A.

PDRG1 (p53 and DNA damage-regulated gene 1) at the interface between intermediary metabolism and oncogenesis.

2017 World Journal of Biological Chemistry

Volumen:

Pagina Inicial:

175

Pagina Final:

186

Autores:
María Ángeles Pajares

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss

2017 Frontiers in Molecular Neuroscience

Volumen:

Pagina Inicial:

107

Pagina Final:

Autores:
Teresa Partearroyo;Néstor Vallecillo;María A. Pajares;Gregorio Varela-Moreiras;Isabel Varela-Nieto

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

2017 Biochimica et Biophysica Acta - Molecular Cell Research

Volumen:

1864

Pagina Inicial:

1165

Pagina Final:

1182

Autores:
Pérez-Miguelsanz, J.;Vallecillo, N.;Garrido, F.;Reytor, E.;Pérez-Sala, D.;Pajares, M.A.

The oncogene PDRG1 is an interaction target of methionine adenosyltransferases.

2016 PLoS ONE

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Pagina Final:

Autores:
Claudia Pérez;Francisco J. Pérez-Zúñiga;Francisco Garrido;Edel Reytor;Francisco Portillo;María A. Pajares

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice

2016 Frontiers in Aging Neuroscience

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Autores:
Raquel Martínez-Vega;Silvia Murillo-Cuesta;Teresa Partearroyo;Gregorio Varela-Moreiras;Isabel Varela-Nieto;María A. Pajares

The new levels of redox regulation of S-adenosylmethionine synthesis

2016 Anales de la Real Academia Nacional de Farmacia

Volumen:

Pagina Inicial:

243

Pagina Final:

258

Autores:
Pajares, M.Á.

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and AldoseReductase

2016 Frontiers in Pharmacology

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Autores:
Francisco J. Sánchez-Gómez;Beatriz Díez-Dacal;ElenaGarcía-Martín;José A. G. Agúndez;Maria A. Pajares;Dolores Pérez-Sala

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism

2015 FASEB Journal

Volumen:

Pagina Inicial:

418

Pagina Final:

432

Autores:
Martínez-Vega, R.;Garrido, F.;Partearroyo, T.;Cediel, R.;Zeisel, S.H.;Martínez-Álvarez, C.;Varela-Moreiras, G.;Varela-Nieto, I.;Pajares, M.A.

Long-term omega-3 fatty acid supplementation ameliorates cochlear homocysteine metabolism and progressive hearing loss in mice.

2015 Journal of Nutritional Biochemistry

Volumen:

Pagina Inicial:

1424

Pagina Final:

1433

Autores:
Martínez-Vega, R.;Murillo-Cuesta, S.;Partearroyo, T.;Varela-Moreiras, G.;Varela-Nieto, I.;Pajares, M.A.

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.

2014 FASEB Journal

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Autores:
Martínez-vega, R;Garrido, F;Partearroyo, T;Cediel, R;Zeisel, SH;Martínez-Álvarez, C;Varela-Moreiras, G;Pajares, MA;varela-nieto, i.

Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes

2014 Antioxidants & Redox Signaling

Volumen:

Pagina Inicial:

2541

Pagina Final:

2554

Autores:
Delgado, M.;Garrido, F.;Pérez-Miguelsanz, J.;Pacheco, M.;Partearroyo, T.;Pérez-Sala, D.;Pajares, M.A.

HOW ARE MAMMALIAN METHIONINE ADENOSYLTRANSFERASES REGULATED IN THE LIVER? A FOCUS ON REDOX STRESS.

2013 FEBS Letters

Volumen:

587

Pagina Inicial:

1711

Pagina Final:

1716

Autores:
María A. Pajares;Luis Álvarez;Dolores Pérez-Sala

Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs

2013 Inflammation and Allergy - Drug Targets

Volumen:

Pagina Inicial:

162

Pagina Final:

171

Autores:
Sánchez-Gómez FJ;García Dorado C;Ayuso P;Agúndez JAG;Pajares MA;Pérez-Sala D

NADP + Binding to the Regulatory Subunit of Methionine Adenosyltransferase II Increases Intersubunit Binding Affinity in the Hetero-Trimer

2012 PLoS ONE

Volumen:

Pagina Inicial:

null

Pagina Final:

Autores:
GonzÃ¡lez, B.;Garrido, F.;Ortega, R.;MartÃnez-JÃºlvez, M.;Revilla-Guarinos, A.;PÃ©rez-Pertejo, Y.;VelÃ¡zquez-Campoy, A.;Sanz-Aparicio, J.;Pajares, M.A.

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride

2012 Amino Acids

Volumen:

Pagina Inicial:

361

Pagina Final:

373

Autores:
Garrido, F;Taylor, JC;Alfonso, C;Markham, GD;Pajares, MA

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride.

2012 Amino Acids

Volumen:

Pagina Inicial:

361

Pagina Final:

373

Autores:
Garrido, F.;Taylor, J.C.;Alfonso, C.;Markham, G.D.;Pajares, M.A.

The relationship between human mat1a mutations and disease: A folding and association problem?

2011 Proteomics Research Journal

Volumen:

Pagina Inicial:

451

Pagina Final:

478

Autores:
Pajares, M.A.;Pérez, C.

Refolding and characterization of methionine adenosyltransferase from Euglena gracilis

2011 Protein Expression and Purification

Volumen:

Pagina Inicial:

128

Pagina Final:

136

Autores:
Garrido, F. ; Estrela, S. ; Alves, C. ; Sánchez-Pérez, G.F. ; Sillero, A. ; Pajares, M.A.

Methionine adenosyltransferase (s-adenosylmethionine synthetase)

2011 Advances in Enzymology and Related Areas of Molecular Biology

Volumen:

Pagina Inicial:

449

Pagina Final:

Autores:
Pajares MA ; Markham GD

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1

2010 Molecular Pharmacology

Volumen:

Pagina Inicial:

723

Pagina Final:

733

Autores:
Sánchez-Gómez, F.J.;Díez-Dacal, B.;Pajares, M.A.;Llorca, O.;Pérez-Sala, D.

Structure-function relationships in methionine adenosyltransferases

2009 Cellular and Molecular Life Sciences

Volumen:

Pagina Inicial:

636

Pagina Final:

648

Autores:
Markham, G.D. ; Pajares, M.A.

Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution

2009 FASEB Journal

Volumen:

Pagina Inicial:

3347

Pagina Final:

3360

Autores:
Reytor, E. ; Pérez-Miguelsanz, J. ; Alvarez, L. ; Pérez-Sala, D. ; Pajares, M.A.

Subunit association as the stabilizing determinant for archaeal methionine adenosyltransferases

2009 Biochimica et Biophysica Acta - Proteins and Proteomics

Volumen:

1794

Pagina Inicial:

1082

Pagina Final:

1090

Autores:
Garrido, F. ; Alfonso, C. ; Taylor, J.C. ; Markham, G.D. ; Pajares, M.A.

Early effects of copper accumulation on methionine metabolism

2008 Cellular and Molecular Life Sciences

Volumen:

Pagina Inicial:

2080

Pagina Final:

2090

Autores:
Delgado, M. ; Pérez-Miguelsanz, J. ; Garrido, F. ; Rodríguez-Tarduchy, G. ; Pérez-Sala, D. ; Pajares, M.A.

Betaine homocysteine S-methyltransferase: Just a regulator of homocysteine metabolism?

2006 Cellular and Molecular Life Sciences

Volumen:

Pagina Inicial:

2792

Pagina Final:

2803

Autores:
Pajares, M.A. ; Pérez-Sala, D.

Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: Insights into intermediate structure through tryptophan substitutions

2005 Biochemical Journal

Volumen:

391

Pagina Inicial:

589

Pagina Final:

599

Autores:
Garrido, F. ; Gasset, M. ; Sanz-Aparicio, J. ; Alfonso, C. ; Pajares, M.A.

Crystal structure of rat liver betaine homocysteine S-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding

2004 Journal of Molecular Biology

Volumen:

338

Pagina Inicial:

771

Pagina Final:

782

Autores:
González, B.;Pajares, M.A.;Martínez-Ripoll, M.;Blundell, T.L.;Sanz-Aparicio, J.

Methionine adenosyltransferase α-helix structure unfolds at lower temperatures than β-sheet: A 2D-IR study

2004 Biophysical Journal

Volumen:

Pagina Inicial:

3951

Pagina Final:

3958

Autores:
Iloro, I.;Chehín, R.;Goñi, F.M.;Pajares, M.A.;Arrondo, J.-L.R.

Cu2+ binding triggers αBoPrP assembly into insoluble laminar polymers

2004 FEBS Letters

Volumen:

556

Pagina Inicial:

161

Pagina Final:

166

Autores:
González-Iglesias, R.;Elvira, G.;Rodríguez-Navarro, J.A.;Vélez, M.;Calero, M.;Pajares, M.A.;Gasset, M.

Methionine adenosyltransferase as a useful molecular systematics tool revealed by phylogenetic and structural analyses

2004 Journal of Molecular Biology

Volumen:

335

Pagina Inicial:

693

Pagina Final:

706

Autores:
Sánchez-Pérez, G.F. ; Bautista, J.M. ; Pajares, M.A.

Role of an intrasubunit disulfide in the association state of the cytosolic homo-oligomer methionine adenosyltransferase

2003 Journal of Biological Chemistry

Volumen:

278

Pagina Inicial:

7285

Pagina Final:

7293

Autores:
Sánchez-Pérez, G.F. ; Gasset, M. ; Calvete, J.J. ; Pajares, M.A.

Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism

2003 Journal of Molecular Biology

Volumen:

331

Pagina Inicial:

407

Pagina Final:

416

Autores:
González, B. ; Pajares, M.A. ; Hermoso, J.A. ; Guillerm, D. ; Guillerm, G. ; Sanz-Aparicio, J.

Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase

2003 Biochemical Journal

Volumen:

370

Pagina Inicial:

945

Pagina Final:

952

Autores:
González, B.;Campillo, N.;Garrido, F.;Gasset, M.;Sanz-Aparicio, J.;Pajares, M.A.

Leishmania donovani methionine adenosyltransferase: Role of cysteine residues in the recombinant enzyme

2003 European Journal of Biochemistry

Volumen:

270

Pagina Inicial:

Pagina Final:

Autores:
Pérez-Pertejo, Y. ; Reguera, R.M. ; Villa, H. ; García-Estrada, C. ; Balaña-Fouce, R. ; Pajares, M.A. ; Ordóñez, D.

Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites

2002 Biochemical Journal

Volumen:

361

Pagina Inicial:

307

Pagina Final:

315

Autores:
Gasset, M. ; Alfonso, C. ; Neira, J.L. ; Rivas, G. ; Pajares, M.A.

Priones: agentes causales de las encefalopatías espongiformes transmisibles.

2002 Medicina Clinica

Volumen:

119

Pagina Inicial:

Pagina Final:

Autores:
González-Iglesias, R.;Espinosa, J. C.;Rodríguez, J. A.;Borniquel, S.;Elvira, G.;Pajares, M. A.;Gasset, M..

Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver

2002 Acta Crystallographica Section D: Biological Crystallography

Volumen:

Pagina Inicial:

1507

Pagina Final:

1510

Autores:
González, B. ; Pajares, M.A. ; Too, H.-P. ; Garrido, F. ; Blundell, T.L. ; Sanz-Aparicio, J.

Prion protein interaction with glycosaminoglycan occurs with the formation of oligomeric complexes stabilized by Cu(II) bridges

2002 Journal of Molecular Biology

Volumen:

319

Pagina Inicial:

527

Pagina Final:

540

Autores:
González-Iglesias, R.;Pajares, M.A.;Ocal, C.;Carlos Espinosa, J.;Oesch, B.;Gasset, M.

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

2000 European Journal of Biochemistry

Volumen:

267

Pagina Inicial:

132

Pagina Final:

137

Autores:
Martínez-Chantar, M.L. ; Pajares, M.A.

The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site

2000 Journal of Molecular Biology

Volumen:

300

Pagina Inicial:

363

Pagina Final:

375

Autores:
González, B. ; Pajares, M.A. ; Hermoso, J.A. ; Alvarez, L. ; Garrido, F. ; Sufrin, J.R. ; Sanz-Aparicio, J.

Refolding and characterization of rat liver methionine adenosyltransferase from Escherichia coli inclusion bodies

2000 Protein Expression and Purification

Volumen:

Pagina Inicial:

219

Pagina Final:

226

Autores:
López-Vara, M.C. ; Gasset, M. ; Pajares, M.A.

Recombinant rat liver S-adenosyl-L-methionine synthetase tetramers and dimers are in equilibrium

1997 International Journal of Biochemistry and Cell Biology

Volumen:

Pagina Inicial:

485

Pagina Final:

491

Autores:
Mingorance, J. ; Alvarez, L. ; Pajares, M.A. ; Mato, J.M.

S-adenosylmethionine synthesis: Molecular mechanisms and clinical implications

1997 Pharmacology and Therapeutics

Volumen:

Pagina Inicial:

265

Pagina Final:

280

Autores:
Mato, J.M. ; Alvarez, L. ; Ortiz, P. ; Pajares, M.A.

Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression

1997 Endocrinology

Volumen:

138

Pagina Inicial:

1251

Pagina Final:

1258

Autores:
Gil, B. ; Pajares, M.A. ; Mato, J.M. ; Alvarez, L.

Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity

1997 Journal of Biological Chemistry

Volumen:

272

Pagina Inicial:

22875

Pagina Final:

22883

Autores:
Alvarez, L. ; Sánchez-Góngora, E. ; Mingorance, J. ; Pajares, M.A. ; Mato, J.M.

Site-directed mutagenesis of rat liver S-adenosylmethionine synthetase: Identification of a cysteine residue critical for the oligomeric state

1996 Biochemical Journal

Volumen:

315

Pagina Inicial:

761

Pagina Final:

766

Autores:
Mingorance, J. ; Alvarez, L. ; Sánchez-Góngora, E. ; Mato, J.M. ; Pajares, M.A.

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

1996 FEBS Letters

Volumen:

397

Pagina Inicial:

293

Pagina Final:

297

Autores:
Martínez-Chantar, M.L. ; Pajares, M.A.

Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis

1996 Journal of Hepatology

Volumen:

Pagina Inicial:

200

Pagina Final:

205

Autores:
Gassó, M. ; Rubio, M. ; Varela, G. ; Cabré, M. ; Caballería, J. ; Alonso, E. ; Deulofem, R. ; Camps, J. ; Giménez, A. ; Pajares, M. ; Parés, A. ; Mato, J.M. ; Rodés, J.

Increased sensitivity to oxidative injury in Chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA

1996 Biochemical Journal

Volumen:

319

Pagina Inicial:

767

Pagina Final:

773

Autores:
Sánchez-Góngora, E. ; Pastorino, J.G. ; Alvarez, L. ; Pajares, M.A. ; García, C. ; Viña, J.R. ; Mato, J.M. ; Farber, J.L.

Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development

1996 Hepatology

Volumen:

Pagina Inicial:

876

Pagina Final:

881

Autores:
Gil, B.;Casado, M.;Pajares, M.A.;Boscá, L.;Mato, J.M.;Martín-Sanz, P.;Alvarez, L.

Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP

1995 Biochemical Journal

Volumen:

308

Pagina Inicial:

565

Pagina Final:

571

Autores:
Deigner, H.P. ; Mato, J.M. ; Pajares, M.A.

Expression of rat liver S-adenosylmethionine synthetase in Escherichia coli results in two active oligomeric forms

1994 Biochemical Journal

Volumen:

301

Pagina Inicial:

557

Pagina Final:

561

Autores:
Alvarez, L. ; Mingorance, J. ; Pajares, M.A. ; Mato, J.M.

S-adenosyl-L-methionine synthetase and methionine metabolism deficiencies in cirrhosis.

1994 Advances in Experimental Medicine and Biology

Volumen:

368

Pagina Inicial:

113

Pagina Final:

117

Autores:
Mato, J. M.;Alvarez, L.;Ortiz, P.;Mingorance, J.;Durán, C.;Pajares, M. A.

Protein kinase C phosphorylation of rat liver S-adenosylmethionine synthetase: Dissociation and production of an active monomer

1994 Biochemical Journal

Volumen:

303

Pagina Inicial:

949

Pagina Final:

955

Autores:
Pajares, M.A. ; Duran, C. ; Corrales, F. ; Mato, J.M.

Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

1992 Journal of Biological Chemistry

Volumen:

267

Pagina Inicial:

17598

Pagina Final:

17605

Autores:
Pajares, M.A. ; Duran, C. ; Corrales, F. ; Pliego, M.M. ; Mato, J.M.

How is rat liver S-adenosylmethionine synthetase regulated?

1992 FEBS Letters

Volumen:

309

Pagina Inicial:

Pagina Final:

Autores:
Pajares, M.A. ; Corrales, F. ; Duran, C. ; Mato, J.M. ; Alvarez, L.

Impairment of Methionine Metabolism in Liver Disease

1992 Clinical Drug Investigation

Volumen:

Pagina Inicial:

Pagina Final:

Autores:
Corrales, F.;Alvarez, L.;Pajares, M.A.;Ortiz, P.;Mato, J.M.

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S- adenosylmethionine synthetase inactivation and attenuates liver injury

1992 Hepatology

Volumen:

Pagina Inicial:

1022

Pagina Final:

1027

Autores:
Corrales, F. ; Gimenez, A. ; Alvarez, L. ; Caballeria, J. ; Pajares, M.A. ; Andreu, H. ; Pares, A. ; Mato, J.M. ; Rodes, J.

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the M(r) deduced from the cDNA sequence and the purified enzyme

1991 FEBS Letters

Volumen:

290

Pagina Inicial:

142

Pagina Final:

146

Autores:
Alvarez, L. ; Asuncion, M. ; Corrales, F. ; Pajares, M.A. ; Mato, J.M.

Inhibition of glutathione synthesis in the liver leads to S-adenosyl-L-methionine synthetase reduction

1991 Hepatology

Volumen:

Pagina Inicial:

528

Pagina Final:

533

Autores:
Corrales, F. ; Ochoa, P. ; Rivas, C. ; Martin-Lomas, M. ; Mato, J.M. ; Pajares, M.A.

The role of cysteine-150 in the structure and activity of rat liver S-adenosyl-L-methionine synthetase

1991 Biochemical Journal

Volumen:

274

Pagina Inicial:

225

Pagina Final:

229

Autores:
Pajares, M.A. ; Corrales, F.J. ; Ochoa, P. ; Mato, J.M.

Fourier transform infrared studies of active-site-methylated rhodopsin -Implications for chromophore-protein interaction, transducin activation, and the reaction pathway.

1991 Biophysical Journal

Volumen:

Pagina Inicial:

640

Pagina Final:

644

Autores:
Ganter, U. M.;Longstaff, C.;Pajares, M. A.;Rando, R. R.;Siebert, F.

Inactivation and dissociation of S-adenosylmethionine synthetase by modification of sulfhydryl groups and its possible occurrence in cirrhosis

1990 Hepatology

Volumen:

Pagina Inicial:

216

Pagina Final:

222

Autores:
Corrales, F. ; Cabrero, C. ; Pajares, M.A. ; Ortiz, P. ; Martin-Duce, A. ; Mato, J.M.

Mechanisms and consequences of the impairment of the Trans-sulphuration pathway in liver disease.

1990 Drugs

Volumen:

Pagina Inicial:

Pagina Final:

Autores:
Mato, J. M.;Corrales, F.;Martín-Duce, A.;Ortiz, P.;Pajares, M. A.;Cabrero, C.

Mechanisms and Consequences of the Impaired Trans-Sulphuration Pathway in Liver Disease: Part I: Biochemical Implications

1990 Drugs

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Pagina Final:

Autores:
Mato, J.M.;Corrales, F.;Martin-Duce, A.;Ortiz, P.;Pajares, M.A.;Cabrero, C.

Calcium-dependent binding between calmodulin and lysozyme.

1989 FEBS Letters

Volumen:

247

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Pagina Final:

Autores:
Fierro, J. F.;Pajares, M. A.;Hardisson, C.

The active-site environment of rhodopsin.

1989 Journal of Biological Chemistry

Volumen:

264

Pagina Inicial:

6804

Pagina Final:

6809

Autores:
Pajares, M. A.;Rando, R. R.

The structural basis of protein kinase C activation by tumor promoters.

1989 Proceedings of the National Academy of Sciences of the United States of America

Volumen:

Pagina Inicial:

9672

Pagina Final:

9676

Autores:
Nakamura, H.;Kishi, Y.;Pajares, M. A.;Rando, R. R.

-Alteraciones de la SAM-sintetasa hepática en cirrosis humana: implicación de los grupos sulfidrilo en la actividad y estructura de la enzima.

1989 Gastroenterologia y Hepatologia

Volumen:

Pagina Inicial:

437

Pagina Final:

441

Autores:
Corrales, F.;Martín-Duce, A.;Pajares, M. A.;Ortiz, P.;Mato, J. M.

Protein Kinase C catalyzes the phosphorylation and activation of rat liver phospholipid methyltransferase.

1987 Biochemical Journal

Volumen:

241

Pagina Inicial:

911

Pagina Final:

916

Autores:
Villalba, M. T;Pajares, M. A.;Renart, M. F.;Mato, J. M.

Purification of phospholipid methyltransferase from rat liver microsomes.

1986 Biochemical Journal

Volumen:

237

Pagina Inicial:

699

Pagina Final:

705

Autores:
Pajares, M. A.;Villalba, M. T.;Mato, J. M.

Modulation by the ratio S-adenosylmethionine/S-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase.

1985 Biochimica et Biophysica Acta

Volumen:

847

Pagina Inicial:

273

Pagina Final:

279

Autores:
Villalba, M. T.;Varela, I.;Mérida, I.;Pajares, M. A.;Martínez del Pozo, A.;Mato, J. M.

Activation of partially purified rat liver lipid methyltransferase by phosphorylation.

1984 Biochemical and Biophysical Research Communications

Volumen:

122

Pagina Inicial:

1065

Pagina Final:

1070

Autores:
Varela, I.;Mérida, I.;Pajares, M.;Villalba, M. T.;Mato, J. M.

How many phospholipid methyltransferases are there in mammalian cells?

1984 Trends in Biochemical Sciences

Volumen:

Pagina Inicial:

471

Pagina Final:

472

Autores:
Mato, J.M.;Pajares, M. A.;Varela, I.

Purification and photoaffinity labeling of lipid methyltransferase from rat liver.

1984 Biochemical Journal

Volumen:

223

Pagina Inicial:

Pagina Final:

Autores:
Pajares, M. A.;Alemany, S.;Varela, I.;Marín Cao, D.;Mato, J. M.