HEPATOBILIARY TUMORS LABORATORY

Our group develops translational research focusing on the study of the pathogenesis and treatment of primary liver cancer, including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). In particular, we are interested in better comprehending the crosstalk interactions between cancer and stromal cells from the tumor microenvironment. We apply our results to discover new therapeutic targets and to develop novel therapies that improve tumor progression. To achieve this, the group uses a wide range of experimental methods, which include analyses of patient samples, unbiased analysis of omics data, 2D and 3D in vitro models of liver cancer and state-of-the-art in vivo models of liver carcinogenesis, where we test new potential therapies.