- Head researcher
- AURA CARREIRA MORENO
Genome Instability and Cancer Predisposition
Our lab studies genome protection using the BRCA2 protein as a model, exploring its role in breast cancer susceptibility. We found new partners of BRCA2 through interaction studies, including RNA helicases. BRCA2 deficiency leads to DNA-RNA hybrids accumulation, which we addressed with the RNA helicase DDX5 collaboration (Sessa et al EMBOJ 2021).
Main specialization
Área de investigación:
Disciplina ERC:
- LS - LIFE SCIENCES
- LS2 Genetics, Genomics, Bioinformatics and Systems Biology
Industrial Leadership:
- 7. Other
- 7.1. Other
Societal Challenges:
- 7. Other
- 7.1. Other