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Stage of development
Prototipe tested in pacients

Intellectual property
PCT application

Intended collaboration
Licensing and/or co-development

Contact
Eva Gabaldón
Vice-presidency for Innovation and Transfer
eva.gabaldon@csic.es
comercializacion@csic.es

Reference
CSIC/EG/118
Additional information
#Health #Medical device #Implantable / Pprosthetic #Neurology #Biotechnology #Biosensor

Control method for a neuroprosthetic device for the reduction of pathological tremors

Monitor and reduce pathological tremors in users through a neuroprosthetic system able to stimulate patient´s affected pathways.

Market need
Tremor is the most common movement disorder and its incidence and prevalence are increasing with the aging of the world population, affecting 15% of people aged between 50 and 89 years. The most common are tremors caused by the two neurodegenerative diseases: Parkinson's disease and Essential tremor. Although the disorder is not life-threatening, more than 65% of population suffering from upper limb tremor reports serious difficulties in performing the activities of daily living (ADL), greatly decreasing their independence and quality of life.

Proposed solution
This is a method for controlling a neuroprosthetic device for the treatment of tremors by modulating the affected afferent pathways. This new method allows the monitoring in real time of the tremorgenic bursts at the peripheral agonist muscle and concomitant stimulation of the antagonist muscle. Monitoring and stimulation are made at the peripheral level (muscles) of the nervous system.

Competitive advantages
  • Avoid the side effects of invasive direct brain stimulation and potentiate the effects of tremor reduction of peripheral stimulation techniques to more than a few minutes post stimulation.
  • Solves the problem of short-term effect of tremor reduction in methods based on peripheral stimulation.
  • Allows customized stimulation through neuroprosthetic systems.