Unit of Synthesis and Biomedical Applications of Peptides

This research group has been working with peptides for over 25 years. The group’s main objective is the chemical synthesis of peptides with biomedical applications. The group has collaborated with other Spanish research groups and also with groups from abroad in different fields, including morphinomimetic peptides, novel alternative cancer treatments, the inhibition of proliferative vitreoretinopathy and peptide vaccines; as well as the use of peptides in the diagnosis of multiple sclerosis, rheumatoid arthritis and both hepatitis A and G. We are currently researching peptide chemistry from three different perspectives: design (lipoderivatives; cyclic multimeric peptides coordinated with gold), synthesis (solid phase and solution) and research into their possible application, both in therapy (HIV entry inhibitors; peptide controlled-release nanosystems for ocular administration of drugs) and in the diagnosis of human diseases (rheumatoid arthritis; HIV/GBV-C co-infection)