Subcellular Calcium Homeostasis

Our group has more than 30 years of experience in the study of intracellular calcium dynamics, especially at the level of intracellular organelles such as mitochondria, endoplasmic reticulum or secretory vesicles. Currently, our group is focused on the model of the nematode C. elegans, and our main interests are: Cytosolic and mitochondrial calcium dynamics in C. elegans worms in vivo and its relationship with the aging process. Study of the effect of modulators of intracellular calcium signaling on longevity and health in C. elegans worms. Effect of these modulators in models of neurodegenerative diseases in C. elegans.