Structural virology and large biological complexes

The research group focuses on the structure-function relationships of a diversity of proteins and macromolecular complexes directly involved in pathological processes. In particular, viral proteins and protein-complexes involved in RNA replication, viral particles and large macromolecular assemblies. The PI is an elected EMBO member and has over 28 years of experience in the area of Structural Biology with > 80 Q1 publications, including papers in high impact factor journals like Nature Structural and Molecular Biology, PNAS or EMBO J, among others and 84 macromolecular structures deposited with the Protein Data Bank. The group uses a number of structural biology techniques, mainly X-ray crystallography and electron microscopy, combined with a broad spectrum of biochemical, biophysical, molecular and cellular biology techniques. Currently, the group consists of 7 members, including 1 research associate, 2 postdocs, 2 PhD students, 1 technician and the PI.