Control of cellular space, morphogenesis and nuclear architecture

The projects conducted in our laboratory are aimed at understanding how cells acquire their characteristic shape and how they maintain nuclear architecture and genomic integrity. To study these questions, we are using a simple eukaryote, genetically tractable fission yeast Schizosaccharomyces pombe, as a model organism. Fission yeast is a useful model for addressing these problems, due to its easy genetics, availability of genome-wide collection of gene deletions and well developed microscopic, genetic and molecular biology tools.