We develop 2 synnergetic research lines: 1.- Materials and devices for the digitalization of society: 0-1-2-3D magnetic, superconductors, ferroelectrics and semiconductors materials and their heterostrcutures with enphasis in highly correlated oxides as the basis for new device concepts that imply the creation of quantum matter at the interfaces and can be manipulated by external stilmuli at the microscopic or macroscopic scales.

Activation of proapoptotic receptors by recombinant TRAIL or agonistic antibodies is currently undergoing clinical trials as a potential therapeutic strategy against solid and hematological tumours. However, there are still many uncertainties regarding the resistance of nontumour cells to TRAIL. Furthermore, a number of studies suggest that primary tumours are also resistant to TRAIL. We are involved in the study of the mechanisms controlling the resistance of normal breast epithelial cells to the apoptotic ligand TRAIL.

We cover a wide range of studies on evolutionary biology, population genetics and comparative genomics systems, from basic biodiversity work on different model and non-model organisms, to projects on compative genomics and bioinformatics.

Research in my laboratory is focused on understanding the molecular mechanisms and cellular functions of proteins and how their defects can lead to disease. We are particularly interested in explaining protein malfunction, in identifying disease-causing variants, and in helping to find new therapeutic strategies to amend the activity of the faulty proteins. My group’s approach relies on a mixture of biochemical and biophysical methods to define the structure, function and evolution of these macromolecular targets.

Our group conducts multidisciplinary research within the Natural Resources Area. We pursue developing an integrative view of functional ecology, built on a combination of approaches in cell biology, physiology, biogeochemistry, material science, bioconservation, biodiversity, and organismal evolution. This fundamental research is complemented with practical objectives.

The Mathematical Modeling and Simulation group is aware of the enormous technological potential of mathematics and seeks to demonstrate it by addressing a wide spectrum of problems with a multidisciplinary mathematical approach, with an emphasis on numerical and computational simulation.

Among ionic channels, those that are potassium selective are, by far, the most diverse group. They play a key role in processes such as immune response, cell differentiation, excitability and cell death, among others. More than 60 genes for potassium channels are known in the human genome, which together with the fact that up to four different subunits can combine to form a channel, means that there are a large numbers of variants.

To identify evolutionary processes related to the origin of Biodiversity, focussed on processes of species formation, hybridization and evolutionary radiations, through diverse geographic scales, in taxononomically complex Arthropds. The formation of cryptic species is a widespread phenomenon in nature, which has a real incidence on animal biodiversity estimates. It has been proposed that the formation of cryptic species is directly related with the existence of divergent phylogeographic (mitochondrial) lineages, and dependent on the time elapsed since the lineages diverged.

Our research group is positioned at MATTER area within the CSIC. Our main line of research is Organic Synthesis. Research in our group is focused on linking the development of synthetic methodology (new reactions, new elements of stereocontrol, etc.) with the synthesis of complex bioactive products.