Identifican un nuevo modelo de desarrollo de la corteza cerebral

La reelina es una proteína crucial en la regulación de la migración neuronal y del posicionamiento de las neuronas durante el desarrollo del cerebro…

IMMUNOREGULATION OF INFECTIOUS, INFLAMMATORY AND NEURODEGENERATIVE DISORDERS

To know the relationship between the central nervous system and the immune system, characterizing the connection between infectious diseases and…

Molecular mechanisms of neurodegeneration

The Neurobiology Unit investigates molecular mechanisms of neuronal death with the aim of identifying targets for therapeutic intervention in…

Mitochondrial regulation of cell death

The group has a long trajectory in oxidative stress and lipid signaling in cell death. In particular, we have described the key role of mitochondrial…

Diagnostic and neuroprotective tools for excitotoxicity and brain ischemia

We are interested in the development of diagnostic strategies and neuroprotective drugs applicable to pathologies associated to the overactivation of…

Laboratorio Cajal de Circuitos Corticales:Microorganization of the normal cerebral cortex and alterations of cortical circuits

Javier DeFelipe’s laboratory has an extensive experience in the analysis on the microorganization of the cerebral cortex using various…

Aging and Neurodegeneration

The goal of our group is to discover new therapeutic strategies to combat the underlying alterations of the cognitive loss in pathological brain…

DEVELOPMENT OF BLOOD BIOMARKERS TO IDENTIFY THE PROCOAGULANT STATE IN ALZHEIMER¿S DISEASE

REGULATION OF SOMATIC NEURONAL TETRAPLOIDY GENERATION DURING ALZHEIMER¿S DISEASE

Studying accelerated brain aging mechanisms in patients with Alzheimer's disease