Type III intermediate filaments as targets and effectors of electrophiles and oxidants

2020 Redox Biology Volume: Pagina Inicial: 101582 Pagina Final: -
Autores: Álvaro Viedma-Poyatos;María A Pajares;Dolores Pérez-Sala

Protein-protein interactions involving enzymes of the mammalian methionine and homocysteine metabolism

2020 Biochimie Volume: Pagina Inicial: 33 Pagina Final: 47
Autores: Portillo, F.;Vázquez, J.;Pajares, M.A.

Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency

2020 Frontiers in Pharmacology Volume: Pagina Inicial: 189 Pagina Final: -
Autores: María A. Pajares;Tahl Zimmerman;Francisco J. Sánchez-Gómez;Adriana Ariza;María J. Torres;Miguel Blanca;F. Javier Cañada;María I. Montañez;Dolores Pérez-Sala

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division.

2019 Nature Communications Volume: Pagina Inicial: 4200 Pagina Final: -
Autores: Duarte, S.;Viedma-Poyatos A.;Navarro-Carrasco, E.;Martínez, A.E.;Pajares, M.A.;Pérez-Sala, D.

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

2019 Redox Biology Volume: Pagina Inicial: - Pagina Final: -
Autores: Andreia Mónico;Sofia Duarte;María A. Pajares;Dolores Pérez-Sala

Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions

2019 Free Radical Biology and Medicine Volume: Pagina Inicial: - Pagina Final: -
Autores: Zorrilla, S.;Mónico, A.;Duarte, S.;Rivas, G.;Pérez-Sala, D.;Pajares, M.A.

Interplay between nutrition and hearing loss: State of art.

2019 Nutrients Volume: Pagina Inicial: 35 Pagina Final: -
Autores: Puga, A. M.;Pajares, M. A.;Varela-Moreiras, G.;Partearroyo, T.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated to plasma hyperhomocysteinemia.

2019 FASEB Journal Volume: Pagina Inicial: 5942 Pagina Final: 5956
Autores: Partearroyo T;Murillo-Cuesta S;Vallecillo N;Bermúdez-Muñoz JM;Rodríguez-de la Rosa L;Mandruzzato G;Celaya AM;Zeisel SH;Pajares MA;Varela-Moreiras G;Varela-Nieto I.

Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels.

2018 Human Mutation Volume: Pagina Inicial: 1081 Pagina Final: 1091
Autores: García-Martín, E.;Sánchez-Gómez, F.J.;Amo, G.;García Menaya, J.;Cordobés, C.;Ayuso, P.;Plaza Serón M.C.;Blanca, M.;Campo, P.;Esguevillas, G.;Pajares, M.A.;Agúndez, J.A.G.;Pérez-Sala, D.

Mammalian sulfur amino acid metabolism: a nexus between redox regulation, nutrition, epigenetics and detoxification.

2018 Antioxidants & Redox Signaling Volume: Pagina Inicial: 408 Pagina Final: 452
Autores: Pajares, M.A.;Pérez-Sala, D.

Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase.

2018 PLoS ONE Volume: Pagina Inicial: e0199472 Pagina Final: -
Autores: Garrido, F.;Pacheco, M.;Vargas-Martínez, R.;Velasco-García, R.;Jorge, I.;Serrano, H.;Portillo, F.;Vázquez, J.;Pajares, M.A.

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss

2017 Frontiers in Molecular Neuroscience Volume: Pagina Inicial: 107 Pagina Final: -
Autores: Teresa Partearroyo;Néstor Vallecillo;María A. Pajares;Gregorio Varela-Moreiras;Isabel Varela-Nieto

PDRG1 (p53 and DNA damage-regulated gene 1) at the interface between intermediary metabolism and oncogenesis.

2017 World Journal of Biological Chemistry Volume: Pagina Inicial: 175 Pagina Final: 186
Autores: María Ángeles Pajares

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

2017 Biochimica et Biophysica Acta - Molecular Cell Research Volume: Pagina Inicial: 1165 Pagina Final: 1182
Autores: Pérez-Miguelsanz, J.;Vallecillo, N.;Garrido, F.;Reytor, E.;Pérez-Sala, D.;Pajares, M.A.

The oncogene PDRG1 is an interaction target of methionine adenosyltransferases.

2016 PLoS ONE Volume: Pagina Inicial: - Pagina Final: -
Autores: Claudia Pérez;Francisco J. Pérez-Zúñiga;Francisco Garrido;Edel Reytor;Francisco Portillo;María A. Pajares

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and AldoseReductase

2016 Frontiers in Pharmacology Volume: Pagina Inicial: - Pagina Final: -
Autores: Francisco J. Sánchez-Gómez;Beatriz Díez-Dacal;ElenaGarcía-Martín;José A. G. Agúndez;Maria A. Pajares;Dolores Pérez-Sala

The new levels of redox regulation of S-adenosylmethionine synthesis

2016 Anales de la Real Academia Nacional de Farmacia Volume: Pagina Inicial: 243 Pagina Final: 258
Autores: Pajares, M.Á.

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice

2016 Frontiers in Aging Neuroscience Volume: Pagina Inicial: - Pagina Final: -
Autores: Raquel Martínez-Vega;Silvia Murillo-Cuesta;Teresa Partearroyo;Gregorio Varela-Moreiras;Isabel Varela-Nieto;María A. Pajares

Long-term omega-3 fatty acid supplementation ameliorates cochlear homocysteine metabolism and progressive hearing loss in mice.

2015 Journal of Nutritional Biochemistry Volume: Pagina Inicial: 1424 Pagina Final: 1433
Autores: Martínez-Vega, R.;Murillo-Cuesta, S.;Partearroyo, T.;Varela-Moreiras, G.;Varela-Nieto, I.;Pajares, M.A.

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism

2015 FASEB Journal Volume: Pagina Inicial: 418 Pagina Final: 432
Autores: Martínez-Vega, R.;Garrido, F.;Partearroyo, T.;Cediel, R.;Zeisel, S.H.;Martínez-Álvarez, C.;Varela-Moreiras, G.;Varela-Nieto, I.;Pajares, M.A.

Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes

2014 Antioxidants & Redox Signaling Volume: Pagina Inicial: 2541 Pagina Final: 2554
Autores: Delgado, M.;Garrido, F.;Pérez-Miguelsanz, J.;Pacheco, M.;Partearroyo, T.;Pérez-Sala, D.;Pajares, M.A.

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.

2014 FASEB Journal Volume: Pagina Inicial: - Pagina Final: -
Autores: Martínez-vega, R;Garrido, F;Partearroyo, T;Cediel, R;Zeisel, SH;Martínez-Álvarez, C;Varela-Moreiras, G;Pajares, MA;varela-nieto, i.

Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs

2013 Inflammation and Allergy - Drug Targets Volume: Pagina Inicial: 162 Pagina Final: 171
Autores: Sánchez-Gómez FJ;García Dorado C;Ayuso P;Agúndez JAG;Pajares MA;Pérez-Sala D

HOW ARE MAMMALIAN METHIONINE ADENOSYLTRANSFERASES REGULATED IN THE LIVER? A FOCUS ON REDOX STRESS.

2013 FEBS Letters Volume: Pagina Inicial: 1711 Pagina Final: 1716
Autores: María A. Pajares;Luis Álvarez;Dolores Pérez-Sala

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride.

2012 Amino Acids Volume: Pagina Inicial: 361 Pagina Final: 373
Autores: Garrido, F.;Taylor, J.C.;Alfonso, C.;Markham, G.D.;Pajares, M.A.

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride

2012 Amino Acids Volume: Pagina Inicial: 361 Pagina Final: 373
Autores: Garrido, F;Taylor, JC;Alfonso, C;Markham, GD;Pajares, MA

NADP + Binding to the Regulatory Subunit of Methionine Adenosyltransferase II Increases Intersubunit Binding Affinity in the Hetero-Trimer

2012 PLoS ONE Volume: Pagina Inicial: null Pagina Final: -
Autores: González, B.;Garrido, F.;Ortega, R.;Martínez-Júlvez, M.;Revilla-Guarinos, A.;Pérez-Pertejo, Y.;Velázquez-Campoy, A.;Sanz-Aparicio, J.;Pajares, M.A.

Methionine adenosyltransferase (s-adenosylmethionine synthetase)

2011 Advances in Enzymology and Related Areas of Molecular Biology Volume: Pagina Inicial: 449 Pagina Final: -
Autores: Pajares MA ; Markham GD

The relationship between human mat1a mutations and disease: A folding and association problem?

2011 Proteomics Research Journal Volume: Pagina Inicial: 451 Pagina Final: 478
Autores: Pajares, M.A.;Pérez, C.

Refolding and characterization of methionine adenosyltransferase from Euglena gracilis

2011 Protein Expression and Purification Volume: Pagina Inicial: 128 Pagina Final: 136
Autores: Garrido, F. ; Estrela, S. ; Alves, C. ; Sánchez-Pérez, G.F. ; Sillero, A. ; Pajares, M.A.

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1

2010 Molecular Pharmacology Volume: Pagina Inicial: 723 Pagina Final: 733
Autores: Sánchez-Gómez, F.J.;Díez-Dacal, B.;Pajares, M.A.;Llorca, O.;Pérez-Sala, D.

Structure-function relationships in methionine adenosyltransferases

2009 Cellular and Molecular Life Sciences Volume: Pagina Inicial: 636 Pagina Final: 648
Autores: Markham, G.D. ; Pajares, M.A.

Subunit association as the stabilizing determinant for archaeal methionine adenosyltransferases

2009 Biochimica et Biophysica Acta - Proteins and Proteomics Volume: Pagina Inicial: 1082 Pagina Final: 1090
Autores: Garrido, F. ; Alfonso, C. ; Taylor, J.C. ; Markham, G.D. ; Pajares, M.A.

Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution

2009 FASEB Journal Volume: Pagina Inicial: 3347 Pagina Final: 3360
Autores: Reytor, E. ; Pérez-Miguelsanz, J. ; Alvarez, L. ; Pérez-Sala, D. ; Pajares, M.A.

Early effects of copper accumulation on methionine metabolism

2008 Cellular and Molecular Life Sciences Volume: Pagina Inicial: 2080 Pagina Final: 2090
Autores: Delgado, M. ; Pérez-Miguelsanz, J. ; Garrido, F. ; Rodríguez-Tarduchy, G. ; Pérez-Sala, D. ; Pajares, M.A.

Betaine homocysteine S-methyltransferase: Just a regulator of homocysteine metabolism?

2006 Cellular and Molecular Life Sciences Volume: Pagina Inicial: 2792 Pagina Final: 2803
Autores: Pajares, M.A. ; Pérez-Sala, D.

Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: Insights into intermediate structure through tryptophan substitutions

2005 Biochemical Journal Volume: Pagina Inicial: 589 Pagina Final: 599
Autores: Garrido, F. ; Gasset, M. ; Sanz-Aparicio, J. ; Alfonso, C. ; Pajares, M.A.

Cu2+ binding triggers αBoPrP assembly into insoluble laminar polymers

2004 FEBS Letters Volume: Pagina Inicial: 161 Pagina Final: 166
Autores: González-Iglesias, R.;Elvira, G.;Rodríguez-Navarro, J.A.;Vélez, M.;Calero, M.;Pajares, M.A.;Gasset, M.

Crystal structure of rat liver betaine homocysteine S-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding

2004 Journal of Molecular Biology Volume: Pagina Inicial: 771 Pagina Final: 782
Autores: González, B.;Pajares, M.A.;Martínez-Ripoll, M.;Blundell, T.L.;Sanz-Aparicio, J.

Methionine adenosyltransferase as a useful molecular systematics tool revealed by phylogenetic and structural analyses

2004 Journal of Molecular Biology Volume: Pagina Inicial: 693 Pagina Final: 706
Autores: Sánchez-Pérez, G.F. ; Bautista, J.M. ; Pajares, M.A.

Methionine adenosyltransferase α-helix structure unfolds at lower temperatures than β-sheet: A 2D-IR study

2004 Biophysical Journal Volume: Pagina Inicial: 3951 Pagina Final: 3958
Autores: Iloro, I.;Chehín, R.;Goñi, F.M.;Pajares, M.A.;Arrondo, J.-L.R.

Leishmania donovani methionine adenosyltransferase: Role of cysteine residues in the recombinant enzyme

2003 European Journal of Biochemistry Volume: Pagina Inicial: 28 Pagina Final: 35
Autores: Pérez-Pertejo, Y. ; Reguera, R.M. ; Villa, H. ; García-Estrada, C. ; Balaña-Fouce, R. ; Pajares, M.A. ; Ordóñez, D.

Role of an intrasubunit disulfide in the association state of the cytosolic homo-oligomer methionine adenosyltransferase

2003 Journal of Biological Chemistry Volume: Pagina Inicial: 7285 Pagina Final: 7293
Autores: Sánchez-Pérez, G.F. ; Gasset, M. ; Calvete, J.J. ; Pajares, M.A.

Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism

2003 Journal of Molecular Biology Volume: Pagina Inicial: 407 Pagina Final: 416
Autores: González, B. ; Pajares, M.A. ; Hermoso, J.A. ; Guillerm, D. ; Guillerm, G. ; Sanz-Aparicio, J.

Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase

2003 Biochemical Journal Volume: Pagina Inicial: 945 Pagina Final: 952
Autores: González, B.;Campillo, N.;Garrido, F.;Gasset, M.;Sanz-Aparicio, J.;Pajares, M.A.

Priones: agentes causales de las encefalopatías espongiformes transmisibles.

2002 Medicina Clinica Volume: Pagina Inicial: 4 Pagina Final: 6
Autores: González-Iglesias, R.;Espinosa, J. C.;Rodríguez, J. A.;Borniquel, S.;Elvira, G.;Pajares, M. A.;Gasset, M..

Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver

2002 Acta Crystallographica Section D: Biological Crystallography Volume: Pagina Inicial: 1507 Pagina Final: 1510
Autores: González, B. ; Pajares, M.A. ; Too, H.-P. ; Garrido, F. ; Blundell, T.L. ; Sanz-Aparicio, J.

Prion protein interaction with glycosaminoglycan occurs with the formation of oligomeric complexes stabilized by Cu(II) bridges

2002 Journal of Molecular Biology Volume: Pagina Inicial: 527 Pagina Final: 540
Autores: González-Iglesias, R.;Pajares, M.A.;Ocal, C.;Carlos Espinosa, J.;Oesch, B.;Gasset, M.

Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites

2002 Biochemical Journal Volume: Pagina Inicial: 307 Pagina Final: 315
Autores: Gasset, M. ; Alfonso, C. ; Neira, J.L. ; Rivas, G. ; Pajares, M.A.

Refolding and characterization of rat liver methionine adenosyltransferase from Escherichia coli inclusion bodies

2000 Protein Expression and Purification Volume: Pagina Inicial: 219 Pagina Final: 226
Autores: López-Vara, M.C. ; Gasset, M. ; Pajares, M.A.

The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site

2000 Journal of Molecular Biology Volume: Pagina Inicial: 363 Pagina Final: 375
Autores: González, B. ; Pajares, M.A. ; Hermoso, J.A. ; Alvarez, L. ; Garrido, F. ; Sufrin, J.R. ; Sanz-Aparicio, J.

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

2000 European Journal of Biochemistry Volume: Pagina Inicial: 132 Pagina Final: 137
Autores: Martínez-Chantar, M.L. ; Pajares, M.A.

S-adenosylmethionine synthesis: Molecular mechanisms and clinical implications

1997 Pharmacology and Therapeutics Volume: Pagina Inicial: 265 Pagina Final: 280
Autores: Mato, J.M. ; Alvarez, L. ; Ortiz, P. ; Pajares, M.A.

Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression

1997 Endocrinology Volume: Pagina Inicial: 1251 Pagina Final: 1258
Autores: Gil, B. ; Pajares, M.A. ; Mato, J.M. ; Alvarez, L.

Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity

1997 Journal of Biological Chemistry Volume: Pagina Inicial: 22875 Pagina Final: 22883
Autores: Alvarez, L. ; Sánchez-Góngora, E. ; Mingorance, J. ; Pajares, M.A. ; Mato, J.M.

Recombinant rat liver S-adenosyl-L-methionine synthetase tetramers and dimers are in equilibrium

1997 International Journal of Biochemistry and Cell Biology Volume: Pagina Inicial: 485 Pagina Final: 491
Autores: Mingorance, J. ; Alvarez, L. ; Pajares, M.A. ; Mato, J.M.

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

1996 FEBS Letters Volume: Pagina Inicial: 293 Pagina Final: 297
Autores: Martínez-Chantar, M.L. ; Pajares, M.A.

Increased sensitivity to oxidative injury in Chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA

1996 Biochemical Journal Volume: Pagina Inicial: 767 Pagina Final: 773
Autores: Sánchez-Góngora, E. ; Pastorino, J.G. ; Alvarez, L. ; Pajares, M.A. ; García, C. ; Viña, J.R. ; Mato, J.M. ; Farber, J.L.

Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis

1996 Journal of Hepatology Volume: Pagina Inicial: 200 Pagina Final: 205
Autores: Gassó, M. ; Rubio, M. ; Varela, G. ; Cabré, M. ; Caballería, J. ; Alonso, E. ; Deulofem, R. ; Camps, J. ; Giménez, A. ; Pajares, M. ; Parés, A. ; Mato, J.M. ; Rodés, J.

Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development

1996 Hepatology Volume: Pagina Inicial: 876 Pagina Final: 881
Autores: Gil, B.;Casado, M.;Pajares, M.A.;Boscá, L.;Mato, J.M.;Martín-Sanz, P.;Alvarez, L.

Site-directed mutagenesis of rat liver S-adenosylmethionine synthetase: Identification of a cysteine residue critical for the oligomeric state

1996 Biochemical Journal Volume: Pagina Inicial: 761 Pagina Final: 766
Autores: Mingorance, J. ; Alvarez, L. ; Sánchez-Góngora, E. ; Mato, J.M. ; Pajares, M.A.

Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP

1995 Biochemical Journal Volume: Pagina Inicial: 565 Pagina Final: 571
Autores: Deigner, H.P. ; Mato, J.M. ; Pajares, M.A.

S-adenosyl-L-methionine synthetase and methionine metabolism deficiencies in cirrhosis.

1994 Advances in Experimental Medicine and Biology Volume: Pagina Inicial: 113 Pagina Final: 117
Autores: Mato, J. M.;Alvarez, L.;Ortiz, P.;Mingorance, J.;Durán, C.;Pajares, M. A.

Protein kinase C phosphorylation of rat liver S-adenosylmethionine synthetase: Dissociation and production of an active monomer

1994 Biochemical Journal Volume: Pagina Inicial: 949 Pagina Final: 955
Autores: Pajares, M.A. ; Duran, C. ; Corrales, F. ; Mato, J.M.

Expression of rat liver S-adenosylmethionine synthetase in Escherichia coli results in two active oligomeric forms

1994 Biochemical Journal Volume: Pagina Inicial: 557 Pagina Final: 561
Autores: Alvarez, L. ; Mingorance, J. ; Pajares, M.A. ; Mato, J.M.

Impairment of Methionine Metabolism in Liver Disease

1992 Clinical Drug Investigation Volume: Pagina Inicial: 8 Pagina Final: 13
Autores: Corrales, F.;Alvarez, L.;Pajares, M.A.;Ortiz, P.;Mato, J.M.

Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

1992 Journal of Biological Chemistry Volume: Pagina Inicial: 17598 Pagina Final: 17605
Autores: Pajares, M.A. ; Duran, C. ; Corrales, F. ; Pliego, M.M. ; Mato, J.M.

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S- adenosylmethionine synthetase inactivation and attenuates liver injury

1992 Hepatology Volume: Pagina Inicial: 1022 Pagina Final: 1027
Autores: Corrales, F. ; Gimenez, A. ; Alvarez, L. ; Caballeria, J. ; Pajares, M.A. ; Andreu, H. ; Pares, A. ; Mato, J.M. ; Rodes, J.

How is rat liver S-adenosylmethionine synthetase regulated?

1992 FEBS Letters Volume: Pagina Inicial: 1 Pagina Final: 4
Autores: Pajares, M.A. ; Corrales, F. ; Duran, C. ; Mato, J.M. ; Alvarez, L.

Inhibition of glutathione synthesis in the liver leads to S-adenosyl-L-methionine synthetase reduction

1991 Hepatology Volume: Pagina Inicial: 528 Pagina Final: 533
Autores: Corrales, F. ; Ochoa, P. ; Rivas, C. ; Martin-Lomas, M. ; Mato, J.M. ; Pajares, M.A.

Fourier transform infrared studies of active-site-methylated rhodopsin -Implications for chromophore-protein interaction, transducin activation, and the reaction pathway.

1991 Biophysical Journal Volume: Pagina Inicial: 640 Pagina Final: 644
Autores: Ganter, U. M.;Longstaff, C.;Pajares, M. A.;Rando, R. R.;Siebert, F.

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the M(r) deduced from the cDNA sequence and the purified enzyme

1991 FEBS Letters Volume: Pagina Inicial: 142 Pagina Final: 146
Autores: Alvarez, L. ; Asuncion, M. ; Corrales, F. ; Pajares, M.A. ; Mato, J.M.

The role of cysteine-150 in the structure and activity of rat liver S-adenosyl-L-methionine synthetase

1991 Biochemical Journal Volume: Pagina Inicial: 225 Pagina Final: 229
Autores: Pajares, M.A. ; Corrales, F.J. ; Ochoa, P. ; Mato, J.M.

Mechanisms and consequences of the impairment of the Trans-sulphuration pathway in liver disease.

1990 Drugs Volume: Pagina Inicial: 58 Pagina Final: 64
Autores: Mato, J. M.;Corrales, F.;Martín-Duce, A.;Ortiz, P.;Pajares, M. A.;Cabrero, C.

Mechanisms and Consequences of the Impaired Trans-Sulphuration Pathway in Liver Disease: Part I: Biochemical Implications

1990 Drugs Volume: Pagina Inicial: 58 Pagina Final: 64
Autores: Mato, J.M.;Corrales, F.;Martin-Duce, A.;Ortiz, P.;Pajares, M.A.;Cabrero, C.

Inactivation and dissociation of S-adenosylmethionine synthetase by modification of sulfhydryl groups and its possible occurrence in cirrhosis

1990 Hepatology Volume: Pagina Inicial: 216 Pagina Final: 222
Autores: Corrales, F. ; Cabrero, C. ; Pajares, M.A. ; Ortiz, P. ; Martin-Duce, A. ; Mato, J.M.

Calcium-dependent binding between calmodulin and lysozyme.

1989 FEBS Letters Volume: Pagina Inicial: 22 Pagina Final: 24
Autores: Fierro, J. F.;Pajares, M. A.;Hardisson, C.

-Alteraciones de la SAM-sintetasa hepática en cirrosis humana: implicación de los grupos sulfidrilo en la actividad y estructura de la enzima.

1989 Gastroenterologia y Hepatologia Volume: Pagina Inicial: 437 Pagina Final: 441
Autores: Corrales, F.;Martín-Duce, A.;Pajares, M. A.;Ortiz, P.;Mato, J. M.

The structural basis of protein kinase C activation by tumor promoters.

1989 Proceedings of the National Academy of Sciences of the United States of America Volume: Pagina Inicial: 9672 Pagina Final: 9676
Autores: Nakamura, H.;Kishi, Y.;Pajares, M. A.;Rando, R. R.

The active-site environment of rhodopsin.

1989 Journal of Biological Chemistry Volume: Pagina Inicial: 6804 Pagina Final: 6809
Autores: Pajares, M. A.;Rando, R. R.

Protein Kinase C catalyzes the phosphorylation and activation of rat liver phospholipid methyltransferase.

1987 Biochemical Journal Volume: Pagina Inicial: 911 Pagina Final: 916
Autores: Villalba, M. T;Pajares, M. A.;Renart, M. F.;Mato, J. M.

Purification of phospholipid methyltransferase from rat liver microsomes.

1986 Biochemical Journal Volume: Pagina Inicial: 699 Pagina Final: 705
Autores: Pajares, M. A.;Villalba, M. T.;Mato, J. M.

Modulation by the ratio S-adenosylmethionine/S-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase.

1985 Biochimica et Biophysica Acta Volume: Pagina Inicial: 273 Pagina Final: 279
Autores: Villalba, M. T.;Varela, I.;Mérida, I.;Pajares, M. A.;Martínez del Pozo, A.;Mato, J. M.

Activation of partially purified rat liver lipid methyltransferase by phosphorylation.

1984 Biochemical and Biophysical Research Communications Volume: Pagina Inicial: 1065 Pagina Final: 1070
Autores: Varela, I.;Mérida, I.;Pajares, M.;Villalba, M. T.;Mato, J. M.

How many phospholipid methyltransferases are there in mammalian cells?

1984 Trends in Biochemical Sciences Volume: Pagina Inicial: 471 Pagina Final: 472
Autores: Mato, J.M.;Pajares, M. A.;Varela, I.

Purification and photoaffinity labeling of lipid methyltransferase from rat liver.

1984 Biochemical Journal Volume: Pagina Inicial: 61 Pagina Final: 66
Autores: Pajares, M. A.;Alemany, S.;Varela, I.;Marín Cao, D.;Mato, J. M.