Genetic approaches to revealing the principles of nuclear architecture

2021 Current Opinion in Genetics and Development Volume: Pagina Inicial: 52 Pagina Final: 60
Autores: Askjaer, P.;Harr, J.C.

Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model

2020 Genes and Development Volume: Pagina Inicial: 560 Pagina Final: 579
Autores: Jennifer C. Harr;Christoph D. Schmid;Celia Muñoz-Jiménez;Raquel Romero-Bueno;Véronique Kalck;Adriana Gonzalez-Sandoval;Michael H. Hauer;Jan Padeken;Peter Askjaer;Anna Mattout;Susan M. Gasser

DamID identifies targets of CEH-60/PBX that are associated with neuron development and muscle structure in Caenorhabditis elegans

2020 PLoS ONE Volume: Pagina Inicial: - Pagina Final: -
Autores: Pieter Van de Walle;Celia Muñoz Jiménez;Peter Askjaer;Liliane Schoofs;Liesbet Temmerman

Nuclear Organization in Stress and Aging

2019 Cells Volume: Pagina Inicial: - Pagina Final: -
Autores: Raquel Romero-Bueno;Patricia de la Cruz Ruiz;Marta Artal-Sanz;Peter Askjaer;Agnieszka Dobrzynska

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation

2019 Cell Death and Differentiation Volume: Pagina Inicial: 1545 Pagina Final: 1565
Autores: David Guerrero-Gómez;José Antonio Mora-Lorca;Beatriz Sáenz-Narciso;Francisco José Naranjo-Galindo;Fernando Muñoz-Lobato;Cristina Parrado-Fernández;Julen Goikolea;Ángel Cedazo-Minguez;Christopher D. Li...et all

Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei

2019 Nature Volume: Pagina Inicial: 734 Pagina Final: 739
Autores: Cabianca, D.S.;Muñoz-Jiménez, C.;Kalck, V.;Gaidatzis, D.;Padeken, J.;Seeber, A.;Askjaer, P.;Gasser, S.M.

CEH-60/PBX regulates vitellogenesis and cuticle permeability through intestinal interaction with UNC-62/MEIS in Caenorhabditis elegans

2019 PLoS Biology Volume: Pagina Inicial: - Pagina Final: -
Autores: Pieter Van de Walle;Ellen Geens;Geert Baggerman;Francisco Jose Naranjo-Galindo;Peter Askjaer;Liliane Schoofs;Liesbet Temmerman

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

2018 BMC Biology Volume: Pagina Inicial: - Pagina Final: -
Autores: Hernando-Rodríguez, B.;Erinjeri, A.P.;Rodríguez-Palero, M.J.;Millar, V.;González-Hernández, S.;Olmedo, M.;Schulze, B.;Baumeister, R.;Muñoz, M.J.;Askjaer, P.;Artal-Sanz, M.

Cell Biology of the Caenorhabditis elegans Nucleus

2017 Genetics Volume: Pagina Inicial: 25 Pagina Final: 59
Autores: Cohen-Fix O;Askjaer P

Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations

2017 Ageing Research Reviews Volume: Pagina Inicial: 18 Pagina Final: 29
Autores: Gonzalo, S.;Kreienkamp, R.;Askjaer, P.

An Efficient FLP-Based Toolkit for Spatiotemporal Control of Gene Expression in Caenorhabditis elegans

2017 Genetics Volume: Pagina Inicial: 1763 Pagina Final: 1778
Autores: Celia Muñoz-Jiménez;Cristina Ayuso;Agnieszka Dobrzynska;Antonio Torres-Mendéz;Patricia de la Cruz Ruiz;Peter Askjaer

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development.

2016 Free Radical Biology and Medicine Volume: Pagina Inicial: 446 Pagina Final: 461
Autores: Mora-Lorca JA;Sáenz-Narciso B;Gaffney CJ;Naranjo-Galindo FJ;Pedrajas JR;Guerrero-Gómez D;Dobrzynska A;Askjaer P;Szewczyk NJ;Cabello J;Miranda-Vizuete A

Lamin binding proteins in Caenorhabditis elegans

2016 Methods in Enzymology Volume: Pagina Inicial: 455 Pagina Final: 483
Autores: Dobrzynska A;Askjaer P;Gruenbaum Y

DamID analysis of nuclear organization in Caenorhabditis elegans

2016 Methods in molecular biology (Clifton, N.J.) Volume: Pagina Inicial: 341 Pagina Final: 358
Autores: Gomez-Saldivar G;Meister P;Askjaer P

The nuclear lamina in health and disease

2016 Nucleus (Austin, Tex.) Volume: Pagina Inicial: 233 Pagina Final: 248
Autores: Dobrzynska, A.;Gonzalo, S.;Shanahan, C.;Askjaer, P.

Identification of Conserved MEL-28/ELYS Domains with Essential Roles in Nuclear Assembly and Chromosome Segregation

2016 PLoS Genetics Volume: Pagina Inicial: - Pagina Final: -
Autores: Gómez-Saldivar, G.;Fernandez, A.;Hirano, Y.;Mauro, M.;Lai, A.;Ayuso, C.;Haraguchi, T.;Hiraoka, Y.;Piano, F.;Askjaer, P.

Functional interplay of two paralogs encoding SWI/SNF chromatin-remodeling accessory subunits during Caenorhabditis elegans development

2016 Genetics Volume: Pagina Inicial: 961 Pagina Final: 975
Autores: Ertl, I.;Porta-De-La-Riva, M.;Gómez-Orte, E.;Rubio-Peña, K.;Corrales, D.;Cornes, E.;Fontrodona, L.;Osteikoetxea, X.;Ayuso, C.;Askjaer, P.;Cabello, J.;Cerón, J.

Chromatids segregate without centrosomes during Caenorhabditis elegans mitosis in a Ran- and CLASP-dependent manner

2015 Molecular Biology of the Cell Volume: Pagina Inicial: 2020 Pagina Final: 2029
Autores: Nahaboo, W.;Zouak, M.;Askjaer, P.;Delattre, M.

Inner nuclear membrane protein LEM-2 is required for correct nuclear separation and morphology in C. elegans

2015 Journal of Cell Science Volume: Pagina Inicial: 1090 Pagina Final: 1096
Autores: Morales-Martínez, A.;Dobrzynska, A.;Askjaer, P.

Age-dependent changes of nuclear morphology are uncoupled from longevity in Caenorhabditis elegans IGF/insulin receptor daf-2 mutants.

2014 Biogerontology Volume: Pagina Inicial: 279 Pagina Final: 288
Autores: Mercedes M. Pérez-Jiménez;María Jesús Rodríguez-Palero;Eduardo Ródenas;Peter Askjaer;Manuel J. Muñoz

Modern techniques for the analysis of chromatin and nuclear organization in C. elegans

2014 WormBook : the online review of C, elegans biology Volume: Pagina Inicial: 1 Pagina Final: -
Autores: Peter Askjaer;Sevinç Ercan;Peter Meister

Modern tools to study nuclear pore complexes and nucleocytoplasmic transport in Caenorhabditis elegans

2014 Methods in Cell Biology Volume: Pagina Inicial: 277 Pagina Final: 310
Autores: Askjaer, P.;Galy, V.;Meister, P.

Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans

2014 GENOME BIOLOGY Volume: Pagina Inicial: null Pagina Final: -
Autores: González-Aguilera, C.;Ikegami, K.;Ayuso, C.;de Luis, A.;Íñiguez, M.;Cabello, J.;Lieb, J.D.;Askjaer, P.

C. elegans epigenetic regulation in development and aging

2014 Briefings in Functional Genomics Volume: Pagina Inicial: 223 Pagina Final: 234
Autores: Cristina Gonzalez-Aguilera;Francesca Palladino;Peter Askjaer

Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans

2014 Genes and Development Volume: Pagina Inicial: 2591 Pagina Final: 2596
Autores: Sharma, R.;Jost, D.;Kind, J.;Gómez-Saldivar, G.;van Steensel, B.;Askjaer, P.;Vaillant, C.;Meister, P.

Dissection of the NUP107 nuclear pore subcomplex reveals a novel interaction with spindle assembly checkpoint protein MAD1 in Caenorhabditis elegans

2012 Molecular Biology of the Cell Volume: Pagina Inicial: 930 Pagina Final: 944
Autores: Ródenas, E.;González-Aguilera, C.;Ayuso, C.;Askjaer, P.

Dissecting the NUP107 complex: Multiple components and even more functions.

2012 Nucleus Volume: Pagina Inicial: - Pagina Final: -
Autores: González-Aguilera C;Askjaer P.

Dissecting the NUP107 complex: multiple components and even more functions.

2012 Nucleus (Austin, Tex.) Volume: Pagina Inicial: 340 Pagina Final: 348
Autores: González-Aguilera, C.;Askjaer, P.

The nucleoporin Nup205/NPP-3 is lost near centrosomes at mitotic onset and can modulate the timing of this process in C. elegans embryos.

2012 Molecular Biology of the Cell Volume: Pagina Inicial: - Pagina Final: -
Autores: Hachet V;Busso C;Toya M;Sugimoto A;Askjaer P;Gönczy P.

The nucleoporin Nup205/NPP-3 is lost near centrosomes at mitotic onset and can modulate the timing of this process in Caenorhabditis elegans embryos

2012 Molecular Biology of the Cell Volume: Pagina Inicial: 3111 Pagina Final: 3121
Autores: Hachet, V.;Busso, C.;Toya, M.;Sugimoto, A.;Askjaer, P.;Gönczy, P.

Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery

2012 Cell Volume: Pagina Inicial: 934 Pagina Final: 947
Autores: Towbin, B.D.;González-Aguilera, C.;Sack, R.;Gaidatzis, D.;Kalck, V.;Meister, P.;Askjaer, P.;Gasser, S.M.

Protein kinase VRK-1 regulates cell invasion and EGL-17/FGF signaling in Caenorhabditis elegans

2009 Developmental Biology Volume: Pagina Inicial: 12 Pagina Final: 21
Autores: Klerkx, E.P.F.;Alarcón, P.;Waters, K.;Reinke, V.;Sternberg, P.W.;Askjaer, P.

Early embryonic requirement for nucleoporin Nup35/NPP-19 in nuclear assembly

2009 Developmental Biology Volume: Pagina Inicial: 399 Pagina Final: 409
Autores: Ródenas, E.;Klerkx, E.P.;Ayuso, C.;Audhya, A.;Askjaer, P.

Emerging biological functions of the vaccinia-related kinase (VRK) family.

2009 Histology and histopathology Volume: Pagina Inicial: 749 Pagina Final: 759
Autores: Klerkx, E.P.;Lazo, P.A.;Askjaer, P.

Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly

2007 EMBO Journal Volume: Pagina Inicial: 132 Pagina Final: 143
Autores: Gorjánácz, M.;Klerkx, E.P.F.;Galy, V.;Santarella, R.;López-Iglesias, C.;Askjaer, P.;Mattaj, I.W.

MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly

2007 EMBO Reports Volume: Pagina Inicial: 165 Pagina Final: 172
Autores: Franz, C.;Walczak, R.;Yavuz, S.;Santarella, R.;Gentzel, M.;Askjaer, P.;Galy, V.;Hetzer, M.;Mattaj, I.W.;Antonin, W.

Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans

2006 Developmental Biology Volume: Pagina Inicial: 360 Pagina Final: 371
Autores: Schetter, A.;Askjaer, P.;Piano, F.;Mattaj, I.;Kemphues, K.

MEL-28, a Novel Nuclear-Envelope and Kinetochore Protein Essential for Zygotic Nuclear-Envelope Assembly in C. elegans

2006 Current Biology Volume: Pagina Inicial: 1748 Pagina Final: 1756
Autores: Galy, V.;Askjaer, P.;Franz, C.;López-Iglesias, C.;Mattaj, I.W.

HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain

2005 Retrovirology Volume: Pagina Inicial: NC Pagina Final: -
Autores: Furnes, C.;Arnesen, T.;Askjaer, P.;Kjems, J.;Szilvay, A.M.

Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates

2005 EMBO Journal Volume: Pagina Inicial: 3519 Pagina Final: 3531
Autores: Franz, C.;Askjaer, P.;Antonin, W.;Iglesias, C.L.;Haselmann, U.;Schelder, M.;De Marco, A.;Wilm, M.;Antony, C.;Mattaj, I.W.

Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex

2004 Molecular Cell Volume: Pagina Inicial: 761 Pagina Final: 775
Autores: Petosa, C.;Schoehn, G.;Askjaer, P.;Bauer, U.;Moulin, M.;Steuerwald, U.;Soler-López, M.;Baudin, F.;Mattaj, I.W.;Müller, C.W.

RanGTP mediates nuclear pore complex assembly

2003 Nature Volume: Pagina Inicial: 689 Pagina Final: 694
Autores: Walther, T.C.;Askjaer, P.;Gentzel, M.;Habermann, A.;Griffiths, G.;Wilm, M.;Mattaj, I.W.;Hetzer, M.

Caenorhabditis elegans Nucleoporins Nup93 and Nup205 Determine the Limit of Nuclear Pore Complex Size Exclusion in Vivo

2003 Molecular Biology of the Cell Volume: Pagina Inicial: 5104 Pagina Final: 5115
Autores: Galy, V.;Mattaj, I.W.;Askjaer, P.

Ran GTpase cycle and importins ¿ and ß are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos

2002 Molecular Biology of the Cell Volume: Pagina Inicial: 4355 Pagina Final: 4370
Autores: Askjaer, P.;Galy, V.;Hannak, E.;Mattaj, I.W.

A role for the basic patch and the C terminus of RanGTP in regulating the dynamic interactions with importin ß, CRM1 and RanBP1

2001 Journal of Molecular Biology Volume: Pagina Inicial: 231 Pagina Final: 243
Autores: Nilsson, J.;Askjaer, P.;Kjems, J.

Rev protein and its cellular partners

2000 Advances in Pharmacology Volume: Pagina Inicial: 251 Pagina Final: 298
Autores: Kjems, J.;Askjaer, P.

Nuclear export of the DEAD box An3 protein by CRM1 is coupled to An3 helicase activity

2000 Journal of Biological Chemistry Volume: Pagina Inicial: 11561 Pagina Final: 11568
Autores: Askjaer, P.;Rosendahl, R.;Kjems, J.

RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase

1999 Molecular and Cellular Biology Volume: Pagina Inicial: 6276 Pagina Final: 6285
Autores: Askjaer, P.;Bachi, A.;Wilm, M.;Bischoff, F.R.;Weeks, D.L.;Ogniewski, V.;Ohno, M.;Niehrs, C.;Kjems, J.;Mattaj, I.W.;Fornerod, M.

Mapping of multiple RNA binding sites of human T-cell lymphotropic virus type I Rex protein within 5'- and 3'-Rex response elements

1998 Journal of Biological Chemistry Volume: Pagina Inicial: 11463 Pagina Final: 11471
Autores: Askjaer, P.;Kjems, J.

The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP

1998 Journal of Biological Chemistry Volume: Pagina Inicial: 33414 Pagina Final: 33422
Autores: Askjaer, P.;Jensen, T.H.;Nilsson, J.;Englmeier, L.;Kjems, J.